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- W3170475145 endingPage "101257" @default.
- W3170475145 startingPage "101257" @default.
- W3170475145 abstract "Therapeutic hypothermia (TH) is now well established to improve intact survival after neonatal encephalopathy (NE). However, many questions could not be addressed by the randomized controlled trials. Should late preterm newborns with NE be cooled? Is cooling beneficial for mild NE? Is the current therapeutic time window optimal, or could it be shortened or prolonged? Will either milder or deeper hypothermia be effective? Does infection/inflammation exposure in the perinatal period in combination with NE offer potentially beneficial preconditioning or might it obviate hypothermic neuroprotection? In the present review, we dissect the evidence, for whom, when and how can TH best be delivered, and highlight areas that need further research." @default.
- W3170475145 created "2021-06-22" @default.
- W3170475145 creator A5024329074 @default.
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- W3170475145 creator A5035285777 @default.
- W3170475145 creator A5046418329 @default.
- W3170475145 creator A5057996190 @default.
- W3170475145 date "2021-10-01" @default.
- W3170475145 modified "2023-10-02" @default.
- W3170475145 title "Unanswered questions regarding therapeutic hypothermia for neonates with neonatal encephalopathy" @default.
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