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- W3171036089 abstract "The lymphatic system plays an integral part in regulating immune cell trafficking and the transport of macromolecules. However, its influence on disease progression and drug uptake is understood less than that of the vascular system. To bridge this knowledge gap, biomaterials can be used to investigate the lymphatic system and to provide novel understanding into complex disease processes, including cancer metastasis and inflammation. Insight gained from these mechanistic studies can be further used to design innovative biomaterials to modulate the immune system, improve drug delivery, and promote tissue regeneration. This review article focuses on recent advances in (i) biomaterials used for lymphatic vessel formation, (ii) models for studying lymphatic-immune cells interactions, (iii) pharmaceuticals and their interactions with the lymphatic system, (iv) and strategies for drug delivery via the lymphatic system. Finally, several challenges regarding adopting biomaterials for immunomodulation and future perspectives are discussed. The lymphatic system plays an integral part in regulating immune cell trafficking and the transport of macromolecules. However, its influence on disease progression and drug uptake is understood less than that of the vascular system. This review article focuses on recent progresses in biomaterials to investigate the lymphatic system and to provide novel understanding into complex disease states. Insight gained from these mechanistic studies can be further used to design innovative biomaterials to modulate the immune system, improve drug delivery, and promote tissue regeneration. Finally, a number of challenges in adopting biomaterials for immunomodulation and future perspectives are discussed." @default.
- W3171036089 created "2021-06-22" @default.
- W3171036089 creator A5044114017 @default.
- W3171036089 creator A5044520397 @default.
- W3171036089 creator A5055298977 @default.
- W3171036089 date "2021-10-01" @default.
- W3171036089 modified "2023-10-14" @default.
- W3171036089 title "Harnessing biomaterials for lymphatic system modulation" @default.
- W3171036089 cites W1527522386 @default.
- W3171036089 cites W1966302921 @default.
- W3171036089 cites W1967127114 @default.
- W3171036089 cites W1967472830 @default.
- W3171036089 cites W1974742442 @default.
- W3171036089 cites W1977784832 @default.
- W3171036089 cites W1978005777 @default.
- W3171036089 cites W1980637669 @default.
- W3171036089 cites W1984678678 @default.
- W3171036089 cites W1986375897 @default.
- W3171036089 cites W1990716542 @default.
- W3171036089 cites W2002375319 @default.
- W3171036089 cites W2013073123 @default.
- W3171036089 cites W2013520568 @default.
- W3171036089 cites W2016021253 @default.
- W3171036089 cites W2016055373 @default.
- W3171036089 cites W2020185478 @default.
- W3171036089 cites W2022258204 @default.
- W3171036089 cites W2026849618 @default.
- W3171036089 cites W2037248548 @default.
- W3171036089 cites W2048883725 @default.
- W3171036089 cites W2056598826 @default.
- W3171036089 cites W2058811019 @default.
- W3171036089 cites W2065373309 @default.
- W3171036089 cites W2065864290 @default.
- W3171036089 cites W2071167287 @default.
- W3171036089 cites W2082602763 @default.
- W3171036089 cites W2083832315 @default.
- W3171036089 cites W2084588802 @default.
- W3171036089 cites W2085444528 @default.
- W3171036089 cites W2090019626 @default.
- W3171036089 cites W2093962834 @default.
- W3171036089 cites W2097471654 @default.
- W3171036089 cites W2115152359 @default.
- W3171036089 cites W2115352852 @default.
- W3171036089 cites W2115533786 @default.
- W3171036089 cites W2121162934 @default.
- W3171036089 cites W2123174763 @default.
- W3171036089 cites W2126951407 @default.
- W3171036089 cites W2129081579 @default.
- W3171036089 cites W2132758299 @default.
- W3171036089 cites W2141747788 @default.
- W3171036089 cites W2144204589 @default.
- W3171036089 cites W2145172700 @default.
- W3171036089 cites W2145354096 @default.
- W3171036089 cites W2145403292 @default.
- W3171036089 cites W2150305156 @default.
- W3171036089 cites W2152239270 @default.
- W3171036089 cites W2155741453 @default.
- W3171036089 cites W2156871373 @default.
- W3171036089 cites W2158137024 @default.
- W3171036089 cites W2158659385 @default.
- W3171036089 cites W2158811925 @default.
- W3171036089 cites W2160335182 @default.
- W3171036089 cites W2174891711 @default.
- W3171036089 cites W2236737199 @default.
- W3171036089 cites W2417772282 @default.
- W3171036089 cites W2418134975 @default.
- W3171036089 cites W2480544051 @default.
- W3171036089 cites W2581171482 @default.
- W3171036089 cites W2584088501 @default.
- W3171036089 cites W2594862203 @default.
- W3171036089 cites W2606107018 @default.
- W3171036089 cites W2608075525 @default.
- W3171036089 cites W2739303686 @default.
- W3171036089 cites W2755067822 @default.
- W3171036089 cites W2787793662 @default.
- W3171036089 cites W2799633834 @default.
- W3171036089 cites W2801427352 @default.
- W3171036089 cites W2903576457 @default.
- W3171036089 cites W2914250487 @default.
- W3171036089 cites W2925912541 @default.
- W3171036089 cites W2927668268 @default.
- W3171036089 cites W2937410951 @default.
- W3171036089 cites W2955437403 @default.
- W3171036089 cites W2999766040 @default.
- W3171036089 cites W3017257173 @default.
- W3171036089 cites W3041375915 @default.
- W3171036089 cites W3046290022 @default.
- W3171036089 cites W3046475322 @default.
- W3171036089 cites W3046560407 @default.
- W3171036089 cites W3047307337 @default.
- W3171036089 cites W3084023066 @default.
- W3171036089 cites W3091646782 @default.
- W3171036089 cites W3094739258 @default.
- W3171036089 cites W3129638514 @default.
- W3171036089 cites W3149941439 @default.
- W3171036089 cites W989751547 @default.
- W3171036089 doi "https://doi.org/10.1016/j.actbio.2021.06.006" @default.
- W3171036089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34118451" @default.