FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3171094564> ?p ?o ?g. }

• W3171094564 endingPage "2474" @default.
• W3171094564 startingPage "2474" @default.
• W3171094564 abstract "Background: premorbid IQ (pIQ) and age of onset are predictors of clinical severity and long-term functioning after a first episode of psychosis. However, the additive influence of these variables on clinical, functional, and recovery rates outcomes is largely unknown. Methods: we characterized 255 individuals who have experienced a first episode of psychosis in four a priori defined subgroups based on pIQ (low pIQ < 85; average pIQ ≥ 85) and age of onset (early onset < 18 years; adult onset ≥ 18 years). We conducted clinical and functional assessments at baseline and at two-year follow-up. We calculated symptom remission and recovery rates using the Positive and Negative Symptoms of Schizophrenia Schedule (PANSS) and the Global Assessment Functioning (GAF or Children-GAF). We examined clinical and functional changes with pair-wise comparisons and two-way mixed ANOVA. We built hierarchical lineal and logistic regression models to estimate the predictive value of the independent variables over functioning or recovery rates. Results: early-onset patients had more severe positive symptoms and poorer functioning than adult-onset patients. At two-year follow-up, only early-onset with low pIQ and adult-onset with average pIQ subgroups differed consistently, with the former having more negative symptoms (d = 0.59), poorer functioning (d = 0.82), lower remission (61% vs. 81.1%), and clinical recovery (34.1% vs. 62.2%). Conclusions: early-onset individuals with low pIQ may present persistent negative symptoms, lower functioning, and less recovery likelihood at two-year follow-up. Intensive cognitive and functional programs for these individuals merit testing to improve long-term recovery rates in this subgroup." @default.
• W3171094564 created "2021-06-22" @default.
• W3171094564 creator A5002872855 @default.
• W3171094564 creator A5004423484 @default.
• W3171094564 creator A5005111955 @default.
• W3171094564 creator A5008273473 @default.
• W3171094564 creator A5017005797 @default.
• W3171094564 creator A5019489574 @default.
• W3171094564 creator A5024775794 @default.
• W3171094564 creator A5026112989 @default.
• W3171094564 creator A5027816426 @default.
• W3171094564 creator A5031344753 @default.
• W3171094564 creator A5040465607 @default.
• W3171094564 creator A5042529801 @default.
• W3171094564 creator A5042973352 @default.
• W3171094564 creator A5050871829 @default.
• W3171094564 creator A5051851273 @default.
• W3171094564 creator A5061926369 @default.
• W3171094564 creator A5068399437 @default.
• W3171094564 creator A5069965531 @default.
• W3171094564 creator A5075521136 @default.
• W3171094564 creator A5079369489 @default.
• W3171094564 creator A5087102006 @default.
• W3171094564 date "2021-06-02" @default.
• W3171094564 modified "2023-10-16" @default.
• W3171094564 title "The Role of Premorbid IQ and Age of Onset as Useful Predictors of Clinical, Functional Outcomes, and Recovery of Individuals with a First Episode of Psychosis" @default.
• W3171094564 cites W1508117510 @default.
• W3171094564 cites W1565231669 @default.
• W3171094564 cites W1584850403 @default.
• W3171094564 cites W1859906091 @default.
• W3171094564 cites W1886403803 @default.
• W3171094564 cites W1964143890 @default.
• W3171094564 cites W1964616687 @default.
• W3171094564 cites W1978367548 @default.
• W3171094564 cites W1982982829 @default.
• W3171094564 cites W1983302342 @default.
• W3171094564 cites W1998582378 @default.
• W3171094564 cites W2001314366 @default.
• W3171094564 cites W2005086832 @default.
• W3171094564 cites W2005970171 @default.
• W3171094564 cites W2011508556 @default.
• W3171094564 cites W2013082031 @default.
• W3171094564 cites W2018054716 @default.
• W3171094564 cites W2022740706 @default.
• W3171094564 cites W2024610939 @default.
• W3171094564 cites W2024624851 @default.
• W3171094564 cites W2050091800 @default.
• W3171094564 cites W2052401826 @default.
• W3171094564 cites W2052963268 @default.
• W3171094564 cites W2058292185 @default.
• W3171094564 cites W2065003979 @default.
• W3171094564 cites W2070752238 @default.
• W3171094564 cites W2074325113 @default.
• W3171094564 cites W2077758934 @default.
• W3171094564 cites W2087591350 @default.
• W3171094564 cites W2097641036 @default.
• W3171094564 cites W2098237864 @default.
• W3171094564 cites W2108080286 @default.
• W3171094564 cites W2108327881 @default.
• W3171094564 cites W2113200491 @default.
• W3171094564 cites W2114776324 @default.
• W3171094564 cites W2115012618 @default.
• W3171094564 cites W2118449279 @default.
• W3171094564 cites W2119226169 @default.
• W3171094564 cites W2120056282 @default.
• W3171094564 cites W2121132206 @default.
• W3171094564 cites W2131925003 @default.
• W3171094564 cites W2132733991 @default.
• W3171094564 cites W2135689380 @default.
• W3171094564 cites W2140606211 @default.
• W3171094564 cites W2141069481 @default.
• W3171094564 cites W2153187258 @default.
• W3171094564 cites W2154167473 @default.
• W3171094564 cites W2156463549 @default.
• W3171094564 cites W2165988750 @default.
• W3171094564 cites W2167441896 @default.
• W3171094564 cites W2169364223 @default.
• W3171094564 cites W2169716279 @default.
• W3171094564 cites W2170551324 @default.
• W3171094564 cites W2172273501 @default.
• W3171094564 cites W2288923216 @default.
• W3171094564 cites W2290263983 @default.
• W3171094564 cites W2304951053 @default.
• W3171094564 cites W2332877535 @default.
• W3171094564 cites W2338861451 @default.
• W3171094564 cites W2339228119 @default.
• W3171094564 cites W2500193007 @default.
• W3171094564 cites W2502511359 @default.
• W3171094564 cites W2567083674 @default.
• W3171094564 cites W2585423456 @default.
• W3171094564 cites W2587074482 @default.
• W3171094564 cites W2608194486 @default.
• W3171094564 cites W2730278132 @default.
• W3171094564 cites W2751792793 @default.
• W3171094564 cites W2763058017 @default.
• W3171094564 cites W2766358153 @default.
• W3171094564 cites W2778974928 @default.
• W3171094564 cites W2887237880 @default.

• next