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- W3171142149 abstract "A series of novel 3-azolylandrosta-3,5-dienes was prepared via Cu-catalyzed Ullmann C–N coupling between a readily available steroidal vinyliodide and a variety of NH-heterocycles. The cytotoxic activity of the target compounds was evaluated against selected cancer cell lines (MCF-7, SKOV-3, DU-145, PC-3). Compound bearing gramine fragment showed the highest antiproliferative effect with IC50 values in the range of 2.0–10.1 μm." @default.
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- W3171142149 date "2021-05-01" @default.
- W3171142149 modified "2023-09-25" @default.
- W3171142149 title "Synthesis of novel cytotoxic 3-azolylsteroids via Cu-catalyzed C–N coupling" @default.
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- W3171142149 doi "https://doi.org/10.1016/j.mencom.2021.04.025" @default.
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