Matches in SemOpenAlex for { <https://semopenalex.org/work/W3171142426> ?p ?o ?g. }
- W3171142426 abstract "Photocoagulation is used for the treatment of retinal ischemic disease. However, due to the invasive nature of photocoagulation and variety of melanin concentrations between individuals, it is challenging to avoid damaging the adjacent photoreceptors and inducing several side effects. Previous studies indicate the role of laser power, duration, and spot size on retinal lesions, but the effect of interspot distance of the laser pulses needs to be considered in panretinal photocoagulation. In this study, we examine different parameters of photocoagulation on lesions of the retina in rabbit, finding that the lesion level of the outer nuclear layer of the retina depended on the pulse duration and laser spot size, and decreasing interspot distance could completely abolish the photoreceptor layer. The degeneration of the photoreceptor by photocoagulation occurred in 24 h and was not restored afterward. We then conducted panretinal photocoagulation in rabbit and found that oxidative stress was decreased in the inner nuclear layer of the retina, and pupillary light reflex and ERG signals were impaired. Our study could provide a rabbit model to explore the mechanism of photoreceptor degeneration and therapies for the side effects after photocoagulation." @default.
- W3171142426 created "2021-06-22" @default.
- W3171142426 creator A5013837286 @default.
- W3171142426 creator A5024461381 @default.
- W3171142426 creator A5026411767 @default.
- W3171142426 creator A5030332534 @default.
- W3171142426 creator A5035669751 @default.
- W3171142426 creator A5058567619 @default.
- W3171142426 creator A5063483943 @default.
- W3171142426 creator A5070046055 @default.
- W3171142426 creator A5076863688 @default.
- W3171142426 date "2021-06-10" @default.
- W3171142426 modified "2023-09-27" @default.
- W3171142426 title "Large-Area Photoreceptor Degeneration Model in Rabbits by Photocoagulation and Oxidative Stress in the Retina" @default.
- W3171142426 cites W1580854974 @default.
- W3171142426 cites W1967799943 @default.
- W3171142426 cites W1978870219 @default.
- W3171142426 cites W1984258230 @default.
- W3171142426 cites W1994148925 @default.
- W3171142426 cites W2003415000 @default.
- W3171142426 cites W2007348919 @default.
- W3171142426 cites W2020824638 @default.
- W3171142426 cites W2021076463 @default.
- W3171142426 cites W2023297446 @default.
- W3171142426 cites W2027957604 @default.
- W3171142426 cites W2037903265 @default.
- W3171142426 cites W2066646623 @default.
- W3171142426 cites W2094860728 @default.
- W3171142426 cites W2094971722 @default.
- W3171142426 cites W2100591312 @default.
- W3171142426 cites W2136919879 @default.
- W3171142426 cites W2148243327 @default.
- W3171142426 cites W2155109647 @default.
- W3171142426 cites W2214361901 @default.
- W3171142426 cites W2219413099 @default.
- W3171142426 cites W2592829086 @default.
- W3171142426 cites W2764178548 @default.
- W3171142426 cites W2768888397 @default.
- W3171142426 cites W2768917396 @default.
- W3171142426 cites W2784682412 @default.
- W3171142426 cites W2793411680 @default.
- W3171142426 cites W2889073711 @default.
- W3171142426 cites W2903448569 @default.
- W3171142426 cites W2922083189 @default.
- W3171142426 doi "https://doi.org/10.3389/fnins.2021.617175" @default.
- W3171142426 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8350927" @default.
- W3171142426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34381331" @default.
- W3171142426 hasPublicationYear "2021" @default.
- W3171142426 type Work @default.
- W3171142426 sameAs 3171142426 @default.
- W3171142426 citedByCount "1" @default.
- W3171142426 countsByYear W31711424262021 @default.
- W3171142426 crossrefType "journal-article" @default.
- W3171142426 hasAuthorship W3171142426A5013837286 @default.
- W3171142426 hasAuthorship W3171142426A5024461381 @default.
- W3171142426 hasAuthorship W3171142426A5026411767 @default.
- W3171142426 hasAuthorship W3171142426A5030332534 @default.
- W3171142426 hasAuthorship W3171142426A5035669751 @default.
- W3171142426 hasAuthorship W3171142426A5058567619 @default.
- W3171142426 hasAuthorship W3171142426A5063483943 @default.
- W3171142426 hasAuthorship W3171142426A5070046055 @default.
- W3171142426 hasAuthorship W3171142426A5076863688 @default.
- W3171142426 hasBestOaLocation W31711424261 @default.
- W3171142426 hasConcept C103796816 @default.
- W3171142426 hasConcept C118487528 @default.
- W3171142426 hasConcept C120665830 @default.
- W3171142426 hasConcept C121332964 @default.
- W3171142426 hasConcept C126322002 @default.
- W3171142426 hasConcept C134018914 @default.
- W3171142426 hasConcept C141071460 @default.
- W3171142426 hasConcept C169760540 @default.
- W3171142426 hasConcept C2776151105 @default.
- W3171142426 hasConcept C2777093970 @default.
- W3171142426 hasConcept C2778231335 @default.
- W3171142426 hasConcept C2779354088 @default.
- W3171142426 hasConcept C2779829184 @default.
- W3171142426 hasConcept C2780827179 @default.
- W3171142426 hasConcept C2781040256 @default.
- W3171142426 hasConcept C2781156865 @default.
- W3171142426 hasConcept C2908627140 @default.
- W3171142426 hasConcept C520434653 @default.
- W3171142426 hasConcept C555293320 @default.
- W3171142426 hasConcept C71924100 @default.
- W3171142426 hasConcept C86803240 @default.
- W3171142426 hasConceptScore W3171142426C103796816 @default.
- W3171142426 hasConceptScore W3171142426C118487528 @default.
- W3171142426 hasConceptScore W3171142426C120665830 @default.
- W3171142426 hasConceptScore W3171142426C121332964 @default.
- W3171142426 hasConceptScore W3171142426C126322002 @default.
- W3171142426 hasConceptScore W3171142426C134018914 @default.
- W3171142426 hasConceptScore W3171142426C141071460 @default.
- W3171142426 hasConceptScore W3171142426C169760540 @default.
- W3171142426 hasConceptScore W3171142426C2776151105 @default.
- W3171142426 hasConceptScore W3171142426C2777093970 @default.
- W3171142426 hasConceptScore W3171142426C2778231335 @default.
- W3171142426 hasConceptScore W3171142426C2779354088 @default.
- W3171142426 hasConceptScore W3171142426C2779829184 @default.
- W3171142426 hasConceptScore W3171142426C2780827179 @default.
- W3171142426 hasConceptScore W3171142426C2781040256 @default.
- W3171142426 hasConceptScore W3171142426C2781156865 @default.