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- W3171505348 abstract "Hamartomatous polyposis syndromes (HPS) are a heterogeneous spectrum of diseases that are characterized by diffuse hamartomatous polyps lining the gastrointestinal (GI) tract together with extra‐GI manifestations. Classical HPS includes juvenile polyposis syndrome, Peutz–Jeghers syndrome, PTEN hamartoma tumor syndrome and hereditary mixed polyposis syndrome. Patients with HPS have a higher risk of GI and extra‐GI malignancies than the general population, although the underlying mechanisms remain unclear and are obviously different from the carcinogenesis of classical adenocarcinoma and colitis‐associated malignancy. In this review we aimed to clarify the risks, possible mechanism and endoscopic surveillance of HPS‐associated GI malignancies." @default.
- W3171505348 created "2021-06-22" @default.
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- W3171505348 date "2021-07-08" @default.
- W3171505348 modified "2023-10-17" @default.
- W3171505348 title "Hamartomatous polyposis syndrome associated malignancies: Risk, pathogenesis and endoscopic surveillance" @default.
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- W3171505348 doi "https://doi.org/10.1111/1751-2980.13029" @default.
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