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• W3171567113 startingPage "533" @default.
• W3171567113 abstract "Cancer is a global health problem associated with genetics and unhealthy lifestyles. Increasingly, pathogenic infections have also been identified as contributors to human cancer initiation and progression. Most pathogens (bacteria, viruses, fungi, and parasites) associated with human cancers are categorized as Group I human carcinogens by the International Agency for Research on Cancer, IARC. These pathogens cause carcinogenesis via three known mechanisms: persistent infection that cause inflammation and DNA damage, initiation of oncogene expression, and immunosuppression activity of the host. In this review, we discuss the carcinogenesis mechanism of ten pathogens, their implications, and some future considerations for better management of the disease. The pathogens and cancers described are Helicobacter pylori (gastric cancer), Epstein-Barr virus (gastric cancer and lymphoma), Hepatitis B and C viruses (liver cancer), Aspergillus spp. (liver cancer), Opisthorchis viverrine (bile duct cancer), Clonorchis sinensis (bile duct cancer), Fusobacterium nucleatum (colorectal cancer), Schistosoma haematobium (bladder cancer); Human Papillomavirus (cervical cancer), and Kaposi’s Sarcoma Herpes Virus (Kaposi’s sarcoma)." @default.
• W3171567113 created "2021-06-22" @default.
• W3171567113 creator A5009457606 @default.
• W3171567113 creator A5010612836 @default.
• W3171567113 creator A5070369262 @default.
• W3171567113 creator A5090761711 @default.
• W3171567113 date "2021-06-15" @default.
• W3171567113 modified "2023-10-10" @default.
• W3171567113 title "Pathogens and Carcinogenesis: A Review" @default.
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