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- W3171599086 endingPage "251525642110166" @default.
- W3171599086 startingPage "251525642110166" @default.
- W3171599086 abstract "Cellular adaptation to stress and metabolic cues requires a coordinated response of different intracellular compartments, separated by semipermeable membranes. One way to facilitate interorganellar communication is via membrane contact sites, physical bridges between opposing organellar membranes formed by an array of tethering machineries. These contact sites are highly dynamic and establish an interconnected organellar network able to quickly respond to external and internal stress by changing size, abundance and molecular architecture. Here, we discuss recent work on nucleus-vacuole junctions, connecting yeast vacuoles with the nucleus. Appearing as small, single foci in mitotic cells, these contacts expand into one enlarged patch upon nutrient exhaustion and entry into quiescence or can be shaped into multiple large foci essential to sustain viability upon proteostatic stress at the nuclear envelope. We highlight the remarkable plasticity and rapid remodelling of these contact sites upon metabolic or proteostatic stress and their emerging importance for cellular fitness." @default.
- W3171599086 created "2021-06-22" @default.
- W3171599086 creator A5002707395 @default.
- W3171599086 creator A5065101054 @default.
- W3171599086 date "2021-01-01" @default.
- W3171599086 modified "2023-10-05" @default.
- W3171599086 title "Remodelling of Nucleus-Vacuole Junctions During Metabolic and Proteostatic Stress" @default.
- W3171599086 cites W1547675180 @default.
- W3171599086 cites W1898232548 @default.
- W3171599086 cites W1969091534 @default.
- W3171599086 cites W1986958303 @default.
- W3171599086 cites W1994390636 @default.
- W3171599086 cites W1994806459 @default.
- W3171599086 cites W1997708732 @default.
- W3171599086 cites W2015031589 @default.
- W3171599086 cites W2032362466 @default.
- W3171599086 cites W2046712075 @default.
- W3171599086 cites W2047373064 @default.
- W3171599086 cites W2047838819 @default.
- W3171599086 cites W2055865419 @default.
- W3171599086 cites W2066029883 @default.
- W3171599086 cites W2074514663 @default.
- W3171599086 cites W2096751414 @default.
- W3171599086 cites W2105769353 @default.
- W3171599086 cites W2111097328 @default.
- W3171599086 cites W2115306772 @default.
- W3171599086 cites W2120507868 @default.
- W3171599086 cites W2123844682 @default.
- W3171599086 cites W2125880822 @default.
- W3171599086 cites W2130337886 @default.
- W3171599086 cites W2134957504 @default.
- W3171599086 cites W2139848107 @default.
- W3171599086 cites W2142437744 @default.
- W3171599086 cites W2143753421 @default.
- W3171599086 cites W2145970367 @default.
- W3171599086 cites W2155982354 @default.
- W3171599086 cites W2160239356 @default.
- W3171599086 cites W2174792969 @default.
- W3171599086 cites W2194950284 @default.
- W3171599086 cites W2284239250 @default.
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- W3171599086 cites W2295347321 @default.
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- W3171599086 cites W2528920961 @default.
- W3171599086 cites W2552607372 @default.
- W3171599086 cites W2570462266 @default.
- W3171599086 cites W2594701333 @default.
- W3171599086 cites W2597223015 @default.
- W3171599086 cites W2608750574 @default.
- W3171599086 cites W2617498609 @default.
- W3171599086 cites W2749141699 @default.
- W3171599086 cites W2750157970 @default.
- W3171599086 cites W2763332188 @default.
- W3171599086 cites W2768672147 @default.
- W3171599086 cites W2784667865 @default.
- W3171599086 cites W2804637674 @default.
- W3171599086 cites W2809901305 @default.
- W3171599086 cites W2884390408 @default.
- W3171599086 cites W2891624903 @default.
- W3171599086 cites W2899277631 @default.
- W3171599086 cites W2900745957 @default.
- W3171599086 cites W2901652858 @default.
- W3171599086 cites W2902536754 @default.
- W3171599086 cites W2906988746 @default.
- W3171599086 cites W2919477878 @default.
- W3171599086 cites W2924515523 @default.
- W3171599086 cites W2929314069 @default.
- W3171599086 cites W2941142795 @default.
- W3171599086 cites W2945010062 @default.
- W3171599086 cites W2954432624 @default.
- W3171599086 cites W2968063196 @default.
- W3171599086 cites W2987979134 @default.
- W3171599086 cites W3006024051 @default.
- W3171599086 cites W3021770362 @default.
- W3171599086 cites W3026097834 @default.
- W3171599086 cites W3030784388 @default.
- W3171599086 cites W3040240159 @default.
- W3171599086 cites W3043252205 @default.
- W3171599086 cites W3043302462 @default.
- W3171599086 cites W3087329937 @default.
- W3171599086 cites W3090305747 @default.
- W3171599086 cites W3093349927 @default.
- W3171599086 cites W3110116128 @default.
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- W3171599086 cites W3114313122 @default.
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- W3171599086 doi "https://doi.org/10.1177/25152564211016608" @default.
- W3171599086 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7610967" @default.
- W3171599086 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34124572" @default.
- W3171599086 hasPublicationYear "2021" @default.
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