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- W3172100024 abstract "Since 2006, the advent of increasingly larger genome-wide association studies and their meta-analyses have led to numerous, replicated findings of genetic polymorphisms associated with many diseases and traits. Early studies suggested that the identified loci generally accounted for a small fraction of the genetic variance estimated from twin and family studies. This led to the concept of ‘missing heritability’. Here, the progress in accounting for a greater proportion of the variance is reviewed. In particular, gene–environment interactions can, for some traits and in certain circumstances, explain part of this missing heritability." @default.
- W3172100024 created "2021-06-22" @default.
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- W3172100024 date "2012-01-01" @default.
- W3172100024 modified "2023-09-23" @default.
- W3172100024 title "Twins and the mystery of missing heritability: the contribution of gene-environment interactions" @default.
- W3172100024 hasPublicationYear "2012" @default.
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