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- W3172327166 abstract "Neurodegeneration with brain iron accumulation (NBIA) is a group of rare neurogenetic degenerative diseases caused by genetic mutations and characterized by iron deposition in the central nervous system, especially in the basal ganglia, with an overall incidence rate of 2/1 000 000-3/1 000 000. Major clinical manifestations are extrapyramidal symptoms. This disease is presently classified into 14 different subtypes based on different pathogenic genes, and its pathogenesis and treatment remain unclear. This article summarizes the research advances in the pathogenesis and treatment of NBIA, so as to help pediatricians understand this disease and provide a reference for subsequent research on treatment." @default.
- W3172327166 created "2021-06-22" @default.
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- W3172327166 date "2021-06-01" @default.
- W3172327166 modified "2023-09-24" @default.
- W3172327166 title "Research advances in the pathogenesis and treatment of neurodegeneration with brain iron accumulation" @default.
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- W3172327166 doi "https://doi.org/10.7499/j.issn.1008-8830.2103149" @default.
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