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- W3172505575 abstract "Abstract Background Factors influencing individual susceptibility to brain acceleration forces or to poor outcomes in brain injury are not well understood. Characterization of blood variants in athletes entering the highly competitive contact environment of professional football, when coupled with longitudinal follow-up of future concussion incidence and trajectory, may provide additional insight into factors that influence brain injury. We observed the metabolic phenotype of collegiate football players entering the 2016 National Football League (NFL) draft. The principal aims were to characterize the molecular status of individual athletes and quantify the prevalence of athletes with multiple concurrent molecular deficits. Methods Blood was taken from 30 elite American collegiate football players seven weeks before the NFL scouting combine and 15-weeks before entering the NFL draft. Results Average results revealed undesirable values in Omega-3 Index (avg ± std, 4.66 ± 1.16 %), AA:EPA fatty acid ratio (29.13 ± 10.78), homocysteine (11.4 ± 3.4 µmol/L), vitamin D (30 ± 11.4 ng/mL), and RBC magnesium (4.1 ± 0.8 mg/dL). Using sport optimized reference ranges from previously published research, 10% presented with 3, 40% presented with 4, and 50% of athletes presented with 5 undesirable values at once. Conclusion We conclude molecular deficits in this cohort entering the NFL draft were common, with a significant number of athletes presenting with multiple abnormalities, all with relevant influence on brain health and function. This data warrants extensive metabolic phenotyping and prophylactic precision nutrition countermeasures for athletes entering contact environments." @default.
- W3172505575 created "2021-06-22" @default.
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- W3172505575 date "2021-04-19" @default.
- W3172505575 modified "2023-09-27" @default.
- W3172505575 title "Molecular Deficits Relevant to Concussion Are Prevalent In Football Players Entering the NFL Draft" @default.
- W3172505575 doi "https://doi.org/10.21203/rs.3.rs-429809/v1" @default.
- W3172505575 hasPublicationYear "2021" @default.
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