FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3172693617> ?p ?o ?g. }

• W3172693617 abstract "We aimed to review relevant randomized controlled trials to assess the relative clinical effects of antibiotic treatment of patients with community-acquired pneumonia (CAP).In this meta-analysis, we identified relevant studies from PubMed, Cochrane, and Embase using appropriate keywords. Key pertinent sources in the literature were also reviewed and all articles published through Oct 2019 were considered for inclusion. For each study, we assessed the risk ratios (RRs) or mean difference combined with the 95% confidence interval (CI) to assess and synthesize outcomes.Overall, 36 studies were consistent with the meta-analysis, involving 17,076 patients. There was no significant difference in the mortality after subgroup analysis: individualized treatment vs. standard treatment; β-lactams plus macrolides vs. β-lactam and/or fluoroquinolone; ceftaroline fosamil vs. ceftriaxone; combination therapy vs. monotherapy or high-dose vs. low-dose. The drug-related adverse event incidence was significantly higher in the ceftriaxone group than in the other drug groups (P<0.05) and also higher in the tigecyline group than in the levofloxacin group (P<0.05). Compared with ceftriaxone, ceftaroline fosamil significantly increased the clinical cure rate at the test-of-cure (TOC) visit in the clinically evaluable population, modified intent-to-treat efficacy (MITTE) population, microbiologically evaluable (ME) population and the microbiological MITTE (mMITTE) population (all P<0.05). Compared with ceftriaxone, ceftaroline fosamil significantly increased the clinical cure rate at the TOC visit in the mMITTE population of Gram positive-Streptococcus pneumoniae (P<0.05) and multidrug-resistant S. pneumoniae (P<0.05).There was a limited number of included studies in the subgroup analysis, but it will still be necessary to conduct more high-quality randomized controlled trials to confirm the clinical efficacy of different antibiotics used to treat CAP." @default.
• W3172693617 created "2021-06-22" @default.
• W3172693617 creator A5002806504 @default.
• W3172693617 creator A5043440739 @default.
• W3172693617 date "2021-06-15" @default.
• W3172693617 modified "2023-10-16" @default.
• W3172693617 title "Comparing Several Treatments with Antibiotics for CommunityAcquired Pneumonia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials" @default.
• W3172693617 cites W1759687512 @default.
• W3172693617 cites W1843993979 @default.
• W3172693617 cites W1966509731 @default.
• W3172693617 cites W1966621081 @default.
• W3172693617 cites W1975569796 @default.
• W3172693617 cites W1991141333 @default.
• W3172693617 cites W1998450970 @default.
• W3172693617 cites W2004627090 @default.
• W3172693617 cites W2013205836 @default.
• W3172693617 cites W2024175754 @default.
• W3172693617 cites W2034247255 @default.
• W3172693617 cites W2055321964 @default.
• W3172693617 cites W2066865250 @default.
• W3172693617 cites W2077548148 @default.
• W3172693617 cites W2100193713 @default.
• W3172693617 cites W2100926508 @default.
• W3172693617 cites W2103633001 @default.
• W3172693617 cites W2115884459 @default.
• W3172693617 cites W2119100503 @default.
• W3172693617 cites W2132212568 @default.
• W3172693617 cites W2150772812 @default.
• W3172693617 cites W2152448836 @default.
• W3172693617 cites W2154159203 @default.
• W3172693617 cites W2155982642 @default.
• W3172693617 cites W2156070290 @default.
• W3172693617 cites W2159069645 @default.
• W3172693617 cites W2169983292 @default.
• W3172693617 cites W2171284117 @default.
• W3172693617 cites W2185366655 @default.
• W3172693617 cites W2191831703 @default.
• W3172693617 cites W2475845335 @default.
• W3172693617 cites W2555418995 @default.
• W3172693617 cites W2626604321 @default.
• W3172693617 cites W2730739597 @default.
• W3172693617 cites W2804875850 @default.
• W3172693617 cites W2828283667 @default.
• W3172693617 cites W2902231090 @default.
• W3172693617 cites W2907290192 @default.
• W3172693617 cites W2916433178 @default.
• W3172693617 cites W2927218701 @default.
• W3172693617 cites W2948202345 @default.
• W3172693617 cites W2948453538 @default.
• W3172693617 cites W2967284043 @default.
• W3172693617 cites W2982145215 @default.
• W3172693617 cites W219020520 @default.
• W3172693617 doi "https://doi.org/10.18502/ijph.v50i6.6410" @default.
• W3172693617 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8410959" @default.
• W3172693617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34540732" @default.
• W3172693617 hasPublicationYear "2021" @default.
• W3172693617 type Work @default.
• W3172693617 sameAs 3172693617 @default.
• W3172693617 citedByCount "2" @default.
• W3172693617 countsByYear W31726936172022 @default.
• W3172693617 crossrefType "journal-article" @default.
• W3172693617 hasAuthorship W3172693617A5002806504 @default.
• W3172693617 hasAuthorship W3172693617A5043440739 @default.
• W3172693617 hasBestOaLocation W31726936171 @default.
• W3172693617 hasConcept C126322002 @default.
• W3172693617 hasConcept C168563851 @default.
• W3172693617 hasConcept C187960798 @default.
• W3172693617 hasConcept C197934379 @default.
• W3172693617 hasConcept C2776102371 @default.
• W3172693617 hasConcept C2776520383 @default.
• W3172693617 hasConcept C2777914695 @default.
• W3172693617 hasConcept C2781253189 @default.
• W3172693617 hasConcept C2781276175 @default.
• W3172693617 hasConcept C2908647359 @default.
• W3172693617 hasConcept C44249647 @default.
• W3172693617 hasConcept C501593827 @default.
• W3172693617 hasConcept C71924100 @default.
• W3172693617 hasConcept C82789193 @default.
• W3172693617 hasConcept C86803240 @default.
• W3172693617 hasConcept C89423630 @default.
• W3172693617 hasConcept C95190672 @default.
• W3172693617 hasConcept C99454951 @default.
• W3172693617 hasConceptScore W3172693617C126322002 @default.
• W3172693617 hasConceptScore W3172693617C168563851 @default.
• W3172693617 hasConceptScore W3172693617C187960798 @default.
• W3172693617 hasConceptScore W3172693617C197934379 @default.
• W3172693617 hasConceptScore W3172693617C2776102371 @default.
• W3172693617 hasConceptScore W3172693617C2776520383 @default.
• W3172693617 hasConceptScore W3172693617C2777914695 @default.
• W3172693617 hasConceptScore W3172693617C2781253189 @default.
• W3172693617 hasConceptScore W3172693617C2781276175 @default.
• W3172693617 hasConceptScore W3172693617C2908647359 @default.
• W3172693617 hasConceptScore W3172693617C44249647 @default.
• W3172693617 hasConceptScore W3172693617C501593827 @default.
• W3172693617 hasConceptScore W3172693617C71924100 @default.
• W3172693617 hasConceptScore W3172693617C82789193 @default.
• W3172693617 hasConceptScore W3172693617C86803240 @default.
• W3172693617 hasConceptScore W3172693617C89423630 @default.
• W3172693617 hasConceptScore W3172693617C95190672 @default.
• W3172693617 hasConceptScore W3172693617C99454951 @default.

• next