FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3172711594> ?p ?o ?g. }

• W3172711594 endingPage "2446" @default.
• W3172711594 startingPage "2437" @default.
• W3172711594 abstract "To compare the safety and efficacy of intrastromal voriconazole (IS-VCZ), amphotericin B (IS-AMB) and natamycin (IS-NTM) as an adjunct to topical natamycin (NTM) in cases of recalcitrant fungal keratitis.Prospective randomized trial.Tertiary eye centre.Sixty eyes of 60 patients with microbiologically proven recalcitrant fungal keratitis (ulcer size >2 mm, depth >50% of stroma, and not responding to topical NTM therapy for two weeks) were recruited.patients were randomized into three groups of 20 eyes, each receiving ISVCZ 50ug/0.1 mL, ISAMB, 5ug/0.1 mL and ISNTM 10ug/0.1 mL (prepared aseptically in ocular pharmacology). The patients in all three groups continued topical NTM 5% every four hours until the ulcer healed. Primary outcome measure was time taken till complete clinical resolution of infection, and secondary outcome measure was best corrected visual acuity (BCVA) at six months.All three groups had comparable baseline parameters. The mean duration of healing was significantly better (p=0.02) in the ISNTM group (34±5.2 days) as compared to the ISVCZ group (36.1±4.8 days) and the ISAMB group (39.2±7.2 days). About 95%, 90% and 95% patients healed successfully in the ISVCZ, ISAMB and ISNTM groups, respectively. In terms of healing, deep vascularization was significantly greater in the ISAMB group (55%, p=0.02) when compared to the ISVCZ and ISNTM groups (31% and 26%, respectively). There were fewer repeat injections in the ISNTM group (7/20 vs 8/20 and 9/20 in the ISVCZ and ISNTM groups, respectively).Intrastromal injections are a safe and effective adjunct to conventional therapy in the management of recalcitrant fungal keratitis. ISNTM had a similar visual outcome with faster healing while ISAMB had a higher rate of deep vascularization after healing." @default.
• W3172711594 created "2021-06-22" @default.
• W3172711594 creator A5014870450 @default.
• W3172711594 creator A5017638830 @default.
• W3172711594 creator A5019869161 @default.
• W3172711594 creator A5020786348 @default.
• W3172711594 creator A5033355902 @default.
• W3172711594 creator A5034045670 @default.
• W3172711594 creator A5047721865 @default.
• W3172711594 creator A5065264820 @default.
• W3172711594 creator A5070023095 @default.
• W3172711594 creator A5070296762 @default.
• W3172711594 creator A5078444378 @default.
• W3172711594 date "2021-06-01" @default.
• W3172711594 modified "2023-09-30" @default.
• W3172711594 title "Comparison of Safety and Efficacy of Intrastromal Injections of Voriconazole, Amphotericin B and Natamycin in Cases of Recalcitrant Fungal Keratitis: A Randomized Controlled Trial" @default.
• W3172711594 cites W1423075642 @default.
• W3172711594 cites W1965219674 @default.
• W3172711594 cites W1969224218 @default.
• W3172711594 cites W1976527660 @default.
• W3172711594 cites W1986938924 @default.
• W3172711594 cites W1990702309 @default.
• W3172711594 cites W2012409544 @default.
• W3172711594 cites W2012818850 @default.
• W3172711594 cites W2032683401 @default.
• W3172711594 cites W204130242 @default.
• W3172711594 cites W2049880056 @default.
• W3172711594 cites W2062103118 @default.
• W3172711594 cites W2076379908 @default.
• W3172711594 cites W2081618734 @default.
• W3172711594 cites W2111283351 @default.
• W3172711594 cites W2114857535 @default.
• W3172711594 cites W2147141118 @default.
• W3172711594 cites W2160234801 @default.
• W3172711594 cites W2409365640 @default.
• W3172711594 cites W2518795767 @default.
• W3172711594 cites W2611764400 @default.
• W3172711594 cites W2773392599 @default.
• W3172711594 cites W2793608126 @default.
• W3172711594 cites W2811230485 @default.
• W3172711594 cites W2923682645 @default.
• W3172711594 cites W3004211781 @default.
• W3172711594 cites W3087746600 @default.
• W3172711594 doi "https://doi.org/10.2147/opth.s301878" @default.
• W3172711594 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8214110" @default.
• W3172711594 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34163127" @default.
• W3172711594 hasPublicationYear "2021" @default.
• W3172711594 type Work @default.
• W3172711594 sameAs 3172711594 @default.
• W3172711594 citedByCount "9" @default.
• W3172711594 countsByYear W31727115942021 @default.
• W3172711594 countsByYear W31727115942022 @default.
• W3172711594 countsByYear W31727115942023 @default.
• W3172711594 crossrefType "journal-article" @default.
• W3172711594 hasAuthorship W3172711594A5014870450 @default.
• W3172711594 hasAuthorship W3172711594A5017638830 @default.
• W3172711594 hasAuthorship W3172711594A5019869161 @default.
• W3172711594 hasAuthorship W3172711594A5020786348 @default.
• W3172711594 hasAuthorship W3172711594A5033355902 @default.
• W3172711594 hasAuthorship W3172711594A5034045670 @default.
• W3172711594 hasAuthorship W3172711594A5047721865 @default.
• W3172711594 hasAuthorship W3172711594A5065264820 @default.
• W3172711594 hasAuthorship W3172711594A5070023095 @default.
• W3172711594 hasAuthorship W3172711594A5070296762 @default.
• W3172711594 hasAuthorship W3172711594A5078444378 @default.
• W3172711594 hasBestOaLocation W31727115941 @default.
• W3172711594 hasConcept C118487528 @default.
• W3172711594 hasConcept C141071460 @default.
• W3172711594 hasConcept C142724271 @default.
• W3172711594 hasConcept C16005928 @default.
• W3172711594 hasConcept C168563851 @default.
• W3172711594 hasConcept C188816634 @default.
• W3172711594 hasConcept C2776079991 @default.
• W3172711594 hasConcept C2776882836 @default.
• W3172711594 hasConcept C2777785397 @default.
• W3172711594 hasConcept C2778257484 @default.
• W3172711594 hasConcept C2778560704 @default.
• W3172711594 hasConcept C2779117757 @default.
• W3172711594 hasConcept C2779548794 @default.
• W3172711594 hasConcept C2779629538 @default.
• W3172711594 hasConcept C2780690907 @default.
• W3172711594 hasConcept C71924100 @default.
• W3172711594 hasConceptScore W3172711594C118487528 @default.
• W3172711594 hasConceptScore W3172711594C141071460 @default.
• W3172711594 hasConceptScore W3172711594C142724271 @default.
• W3172711594 hasConceptScore W3172711594C16005928 @default.
• W3172711594 hasConceptScore W3172711594C168563851 @default.
• W3172711594 hasConceptScore W3172711594C188816634 @default.
• W3172711594 hasConceptScore W3172711594C2776079991 @default.
• W3172711594 hasConceptScore W3172711594C2776882836 @default.
• W3172711594 hasConceptScore W3172711594C2777785397 @default.
• W3172711594 hasConceptScore W3172711594C2778257484 @default.
• W3172711594 hasConceptScore W3172711594C2778560704 @default.
• W3172711594 hasConceptScore W3172711594C2779117757 @default.
• W3172711594 hasConceptScore W3172711594C2779548794 @default.
• W3172711594 hasConceptScore W3172711594C2779629538 @default.
• W3172711594 hasConceptScore W3172711594C2780690907 @default.
• W3172711594 hasConceptScore W3172711594C71924100 @default.

• next