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- W3173185191 endingPage "3064" @default.
- W3173185191 startingPage "3040" @default.
- W3173185191 abstract "Digestive systems in human, animals, and fish are biological reactors and membranes to digest food and extract nutrients. Therefore, static and dynamic models of in-vitro digestion systems are developed to study e.g. novel food and feed before in-vivo studies. Such models are well developed for human, but not to the same extent for animals and fish. On the other hand, recent advances in aquaculture nutrition have created several potential fish meal replacements, and the assessment of their nutrient digestibility is critical in the application as a fish meal replacement. Using an in-vitro method, the assessment of an ingredient digestibility could be faster and less expensive compared to using an in-vivo experiment. An in-vitro method has been widely used to assess food nutrient digestibility for humans; however, its application for fish is still in the early stages. Both the human and fish as monogastric vertebrates share similar gastrointestinal systems; thus, the concept from the application for humans could be applied for fish. This review aims to improve the in-vitro digestion protocol for fish by adapting the concept from then study for humans, summarizing the current available in-vitro digestion model developed for human and fish in-vitro digestion study, identifying challenges specifically for fish required to be tackled and suggesting an engineering approach to adapt the human in-vitro gastrointestinal model to fish. Protocols to conduct in-vitro digestion study for fish are then proposed." @default.
- W3173185191 created "2021-07-05" @default.
- W3173185191 creator A5037864407 @default.
- W3173185191 creator A5041929907 @default.
- W3173185191 creator A5059831254 @default.
- W3173185191 creator A5069380204 @default.
- W3173185191 date "2021-01-01" @default.
- W3173185191 modified "2023-10-01" @default.
- W3173185191 title "<i>In-vitro</i> digestion models: a critical review for human and fish and a protocol for <i>in-vitro</i> digestion in fish" @default.
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