FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3173329168> ?p ?o ?g. }

• W3173329168 endingPage "5222" @default.
• W3173329168 startingPage "5211" @default.
• W3173329168 abstract "Cervical cancer (CC) is the fourth most common cancer among women worldwide. We aimed to explore the role of hsa_circ_000543 played in CC.The hsa_circ_000543 expressions in CC tissues and cells were measured by qRT-PCR. The correlation of hsa_circ_000543 expression and the clinical features of CC patients were analyzed by SPSS 20.0. The up- or down-regulated plasmids of hsa_circ_000543 were respectively transfected into CC cells. Cell proliferation, apoptosis and colony formation were detected through CCK-8 assay, flow cytometry and cell colony formation assay, respectively. The cell migration and invasion were evaluated by Transwell assay. The underlying molecular mechanism of hsa_circ_000543 was studied by bioinformatic prediction tools and luciferase reporter assay. Rescue experiments were performed to validate the regulation mechanism of hsa_circ_000543/miR-567/ZNF268 axis in CC.Hsa_circ_000543 was over-expressed in CC tissues and cells. The high expression of hsa_circ_000543 indicated poor prognosis of CC patients. Hsa_circ_000543 promoted cell proliferation, colony formation, migration and invasion, as well as inhibited cell apoptosis in CC cells. Hsa_circ_000543 directly targeted miR-567/ZNF268 in CC cell lines. In CC tumor tissues and cells, the hsa_circ_000543 expression was negatively correlated with miR-567 expression and showed a positive correlation with ZNF268 expression. The rescue experiments revealed that hsa_circ_000543 mediated cell proliferation, apoptosis, colony formation, migration and invasion of CC cells via regulating miR-567/ZNF268 axis.Hsa_circ_000543 regulated CC cell activities through binding miR-567 and therefore enhancing ZNF268 expression." @default.
• W3173329168 created "2021-07-05" @default.
• W3173329168 creator A5004331784 @default.
• W3173329168 creator A5004858645 @default.
• W3173329168 creator A5067902500 @default.
• W3173329168 creator A5070843765 @default.
• W3173329168 date "2021-06-01" @default.
• W3173329168 modified "2023-10-16" @default.
• W3173329168 title "Hsa_circRNA_000543 Predicts Poor Prognosis and Promotes Cervical Cancer Cell Progression Through Regulating miR-567/ZNF268 Axis" @default.
• W3173329168 cites W1983916388 @default.
• W3173329168 cites W2027789017 @default.
• W3173329168 cites W2049519900 @default.
• W3173329168 cites W2074919458 @default.
• W3173329168 cites W2079172413 @default.
• W3173329168 cites W2082177123 @default.
• W3173329168 cites W2155460954 @default.
• W3173329168 cites W2566881606 @default.
• W3173329168 cites W2600185569 @default.
• W3173329168 cites W2611332446 @default.
• W3173329168 cites W2613179596 @default.
• W3173329168 cites W2809927600 @default.
• W3173329168 cites W2888223281 @default.
• W3173329168 cites W2889646458 @default.
• W3173329168 cites W2909340392 @default.
• W3173329168 cites W2910160623 @default.
• W3173329168 cites W2910599425 @default.
• W3173329168 cites W2912017471 @default.
• W3173329168 cites W2940851111 @default.
• W3173329168 cites W2944376344 @default.
• W3173329168 cites W2946643421 @default.
• W3173329168 cites W2955511511 @default.
• W3173329168 cites W2993250673 @default.
• W3173329168 cites W2999007816 @default.
• W3173329168 cites W3000973529 @default.
• W3173329168 cites W3002003499 @default.
• W3173329168 cites W3014505390 @default.
• W3173329168 cites W3040514712 @default.
• W3173329168 doi "https://doi.org/10.2147/cmar.s302201" @default.
• W3173329168 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8256719" @default.
• W3173329168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34234564" @default.
• W3173329168 hasPublicationYear "2021" @default.
• W3173329168 type Work @default.
• W3173329168 sameAs 3173329168 @default.
• W3173329168 citedByCount "5" @default.
• W3173329168 countsByYear W31733291682022 @default.
• W3173329168 countsByYear W31733291682023 @default.
• W3173329168 crossrefType "journal-article" @default.
• W3173329168 hasAuthorship W3173329168A5004331784 @default.
• W3173329168 hasAuthorship W3173329168A5004858645 @default.
• W3173329168 hasAuthorship W3173329168A5067902500 @default.
• W3173329168 hasAuthorship W3173329168A5070843765 @default.
• W3173329168 hasBestOaLocation W31733291681 @default.
• W3173329168 hasConcept C121608353 @default.
• W3173329168 hasConcept C137738243 @default.
• W3173329168 hasConcept C1491633281 @default.
• W3173329168 hasConcept C153911025 @default.
• W3173329168 hasConcept C185592680 @default.
• W3173329168 hasConcept C190283241 @default.
• W3173329168 hasConcept C502942594 @default.
• W3173329168 hasConcept C54009773 @default.
• W3173329168 hasConcept C54355233 @default.
• W3173329168 hasConcept C553184892 @default.
• W3173329168 hasConcept C55493867 @default.
• W3173329168 hasConcept C62112901 @default.
• W3173329168 hasConcept C81885089 @default.
• W3173329168 hasConcept C86803240 @default.
• W3173329168 hasConcept C96232424 @default.
• W3173329168 hasConceptScore W3173329168C121608353 @default.
• W3173329168 hasConceptScore W3173329168C137738243 @default.
• W3173329168 hasConceptScore W3173329168C1491633281 @default.
• W3173329168 hasConceptScore W3173329168C153911025 @default.
• W3173329168 hasConceptScore W3173329168C185592680 @default.
• W3173329168 hasConceptScore W3173329168C190283241 @default.
• W3173329168 hasConceptScore W3173329168C502942594 @default.
• W3173329168 hasConceptScore W3173329168C54009773 @default.
• W3173329168 hasConceptScore W3173329168C54355233 @default.
• W3173329168 hasConceptScore W3173329168C553184892 @default.
• W3173329168 hasConceptScore W3173329168C55493867 @default.
• W3173329168 hasConceptScore W3173329168C62112901 @default.
• W3173329168 hasConceptScore W3173329168C81885089 @default.
• W3173329168 hasConceptScore W3173329168C86803240 @default.
• W3173329168 hasConceptScore W3173329168C96232424 @default.
• W3173329168 hasLocation W31733291681 @default.
• W3173329168 hasLocation W31733291682 @default.
• W3173329168 hasLocation W31733291683 @default.
• W3173329168 hasOpenAccess W3173329168 @default.
• W3173329168 hasPrimaryLocation W31733291681 @default.
• W3173329168 hasRelatedWork W2345180005 @default.
• W3173329168 hasRelatedWork W2354128257 @default.
• W3173329168 hasRelatedWork W2354735832 @default.
• W3173329168 hasRelatedWork W2355259601 @default.
• W3173329168 hasRelatedWork W2365530377 @default.
• W3173329168 hasRelatedWork W2371611592 @default.
• W3173329168 hasRelatedWork W2381657842 @default.
• W3173329168 hasRelatedWork W2386605958 @default.
• W3173329168 hasRelatedWork W2386797884 @default.
• W3173329168 hasRelatedWork W2392234861 @default.
• W3173329168 hasVolume "Volume 13" @default.

• next