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• W3173453525 endingPage "672" @default.
• W3173453525 startingPage "662" @default.
• W3173453525 abstract "Chromosome 1q often has been observed to be amplified in hepatocellular carcinoma. This review summarizes literature reports of multiple genes that have been proposed as possible 1q amplification drivers. These largely fall within 1q21-1q23. In addition, publicly available copy number alteration data from The Cancer Genome Atlas project were used to identify additional candidate genes involved in carcinogenesis. The most frequent location for gene amplification was 1q22, consistent with the results of the literature search. The genes TPM3 and NUF2 were found to be candidates whose amplification and/or mRNA up-regulation was most highly associated with poorer hepatocellular carcinoma outcomes." @default.
• W3173453525 created "2021-07-05" @default.
• W3173453525 creator A5002876596 @default.
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• W3173453525 date "2021-06-27" @default.
• W3173453525 modified "2023-09-27" @default.
• W3173453525 title "Role of chromosome 1q copy number variation in hepatocellular carcinoma" @default.
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• W3173453525 doi "https://doi.org/10.4254/wjh.v13.i6.662" @default.
• W3173453525 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8239492" @default.
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• W3173453525 hasPublicationYear "2021" @default.
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