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• W3173602007 abstract "Objective — to study the state of iodine supply in children with chronic gastroduodenal pathology.&#x0D; Materials and methods. The study included 23 children with chronic gastroduodenitis: 13 girls (56 %) and 10 boys (43.5 %) aged 8 to 18 years. The control group consisted of 11 children matched in age and sex. All patients underwent endoscopic examination of the upper digestive tract. H. pylori infection was tested with a rapid urease breathing test «Helik‑test». All children underwent determination of iodine level in single portions of urine using the cerium‑arsenite method Sandell‑Koltoff modified by Dunn, with the following calculation of the median.&#x0D; Results. The frequency of iodine deficiency in children with chronic gastroduodenitis was 60.9 ± 10.2 %, which significantly exceeded this parameter in the control group (8.7 ± 8.6 %; p < 0.01). A mild degree of iodine deficiency was noted in 43.5 ± 10.3 % of patients, which was also significantly higher than in the control group (9.09 ± 8.6 %; p < 0.05). Moderate iodine deficiency was observed only in children of the main group (21.7 ± 8.5 %). Severe iodine deficiency in the study was not found among all children. The median ioduria in patients was 81.9 mg/l, which was significantly lower than in children in control group (183.7 mg/l; p < 0.05). Analysis of ioduria level, taking into consideration the endoscopic picture of gastrointestinal tract lesions, showed that both in frequency (p < 0.05) and median (p < 0.05), children with a more severe inflammation of the gastric mucosa and duodenum had the worst indices of iodine supply. In children infected with H. pylori iodine deficiency was observed significantly more often (p < 0.05), the median ioduria was significantly lower (p < 0.05) than in uninfected children.&#x0D; Conclusions. In children with chronic gastroduodenal pathology, a significant frequency of iodine deficiency is revealed, which increases with the severity of inflammatory changes in the mucous membrane and the presence of H. pylori infection. Determination of the state of iodine supply in children with digestive tract pathology is advisable to prevent the development of concomitant diseases, primarily thyroid dysfunction.&#x0D;" @default.
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• W3173602007 date "2021-06-29" @default.
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• W3173602007 title "State of iodine supply in children with chronic gastroduodenitis" @default.
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• W3173602007 doi "https://doi.org/10.30978/mg-2021-3-13" @default.
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