FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3173670054> ?p ?o ?g. }

• W3173670054 abstract "ABSTRACT Background and Objectives Establishing the etiology of community-acquired pneumonia (CAP) in children at admission is challenging. As a result, most children receive antibiotics that do not need. This study aims to build and validate a diagnostic tool combining clinical, analytical and radiographical features to sequentially differentiate viral from bacterial CAP, and among bacterial CAP, typical from atypical bacteria, to improve choice of treatment. Methods Consecutive hospitalized children between 1 month and 16 years of age with CAP were enrolled. An extensive microbiological workup was performed. A score was built with a training set of 70% patients, to first differentiate between viral and bacterial CAP and secondly, typical from atypical bacterial CAP. To select variables, a Ridge model was used. Optimal cut-off points were selected to maximize specificity setting a high sensitivity (80%). Weights of each variable were calculated with a multivariable logistic regression. The score was validated with the rest of the participants. Results In total, 262 (53%) children (median age, 2 years, 52.3% male) had an etiological diagnosis. The step 1 discriminates viral from bacterial CAP. Bacterial CAPs were classified with a sensitivity=97%, a specificity=48%, and a ROC’s area under the curve (AUC)=0.81. If a CAP was classificated as bacterial, it was assessed with step 2. The step 2 differentiates typical vs. atypical bacterial CAP. Typical bacteria were classified with a sensitivity=100%, a specificity=64%, and AUC=0.90. Conclusion This two-steps tool can facilitate the physician’s decision to prescribe antibiotics without compromising patient safety. Article summary We validated a clinical tool to predict the aetiology of CAP in children safely. This tool differentiates CAP into viral, atypical bacteria and typical bacteria. “What’s Known on This Subject” Establishing the aetiology of community-acquired pneumonia (CAP) in children at admission is challenging. As a result, most admitted children with CAP receive antibiotics. “What This Study Adds” We validated a clinical tool to predict the aetiology of pneumonia in children safely, differentiating among viral, atypical bacteria and typical bacteria." @default.
• W3173670054 created "2021-07-05" @default.
• W3173670054 creator A5001548025 @default.
• W3173670054 creator A5005266584 @default.
• W3173670054 creator A5009332129 @default.
• W3173670054 creator A5012649381 @default.
• W3173670054 creator A5012990972 @default.
• W3173670054 creator A5013013637 @default.
• W3173670054 creator A5021374144 @default.
• W3173670054 creator A5021894635 @default.
• W3173670054 creator A5022779122 @default.
• W3173670054 creator A5023797791 @default.
• W3173670054 creator A5026532124 @default.
• W3173670054 creator A5026954959 @default.
• W3173670054 creator A5027081759 @default.
• W3173670054 creator A5027186367 @default.
• W3173670054 creator A5027258827 @default.
• W3173670054 creator A5027357558 @default.
• W3173670054 creator A5027901784 @default.
• W3173670054 creator A5034085532 @default.
• W3173670054 creator A5035912701 @default.
• W3173670054 creator A5038857834 @default.
• W3173670054 creator A5045107856 @default.
• W3173670054 creator A5046556606 @default.
• W3173670054 creator A5047248287 @default.
• W3173670054 creator A5047421296 @default.
• W3173670054 creator A5051886488 @default.
• W3173670054 creator A5055748703 @default.
• W3173670054 creator A5055820345 @default.
• W3173670054 creator A5059535736 @default.
• W3173670054 creator A5066924038 @default.
• W3173670054 creator A5068349028 @default.
• W3173670054 creator A5069494169 @default.
• W3173670054 creator A5072522203 @default.
• W3173670054 creator A5072969181 @default.
• W3173670054 creator A5073632868 @default.
• W3173670054 creator A5076903945 @default.
• W3173670054 creator A5077844706 @default.
• W3173670054 creator A5078157184 @default.
• W3173670054 creator A5078213087 @default.
• W3173670054 creator A5078369109 @default.
• W3173670054 creator A5080231718 @default.
• W3173670054 creator A5085203648 @default.
• W3173670054 creator A5086040475 @default.
• W3173670054 creator A5087432966 @default.
• W3173670054 creator A5091244553 @default.
• W3173670054 date "2021-06-25" @default.
• W3173670054 modified "2023-10-01" @default.
• W3173670054 title "A tool to distinguish viral from bacterial pneumonia" @default.
• W3173670054 cites W1979106746 @default.
• W3173670054 cites W1993486295 @default.
• W3173670054 cites W2014825503 @default.
• W3173670054 cites W2063566130 @default.
• W3173670054 cites W2100451798 @default.
• W3173670054 cites W2100971877 @default.
• W3173670054 cites W2101321064 @default.
• W3173670054 cites W2116581803 @default.
• W3173670054 cites W2124750719 @default.
• W3173670054 cites W2128406535 @default.
• W3173670054 cites W2145271753 @default.
• W3173670054 cites W2610875577 @default.
• W3173670054 cites W2620538498 @default.
• W3173670054 cites W2766582752 @default.
• W3173670054 cites W2926242485 @default.
• W3173670054 cites W2939422634 @default.
• W3173670054 cites W2944437597 @default.
• W3173670054 cites W4239909494 @default.
• W3173670054 doi "https://doi.org/10.1101/2021.06.22.21259301" @default.
• W3173670054 hasPublicationYear "2021" @default.
• W3173670054 type Work @default.
• W3173670054 sameAs 3173670054 @default.
• W3173670054 citedByCount "0" @default.
• W3173670054 crossrefType "posted-content" @default.
• W3173670054 hasAuthorship W3173670054A5001548025 @default.
• W3173670054 hasAuthorship W3173670054A5005266584 @default.
• W3173670054 hasAuthorship W3173670054A5009332129 @default.
• W3173670054 hasAuthorship W3173670054A5012649381 @default.
• W3173670054 hasAuthorship W3173670054A5012990972 @default.
• W3173670054 hasAuthorship W3173670054A5013013637 @default.
• W3173670054 hasAuthorship W3173670054A5021374144 @default.
• W3173670054 hasAuthorship W3173670054A5021894635 @default.
• W3173670054 hasAuthorship W3173670054A5022779122 @default.
• W3173670054 hasAuthorship W3173670054A5023797791 @default.
• W3173670054 hasAuthorship W3173670054A5026532124 @default.
• W3173670054 hasAuthorship W3173670054A5026954959 @default.
• W3173670054 hasAuthorship W3173670054A5027081759 @default.
• W3173670054 hasAuthorship W3173670054A5027186367 @default.
• W3173670054 hasAuthorship W3173670054A5027258827 @default.
• W3173670054 hasAuthorship W3173670054A5027357558 @default.
• W3173670054 hasAuthorship W3173670054A5027901784 @default.
• W3173670054 hasAuthorship W3173670054A5034085532 @default.
• W3173670054 hasAuthorship W3173670054A5035912701 @default.
• W3173670054 hasAuthorship W3173670054A5038857834 @default.
• W3173670054 hasAuthorship W3173670054A5045107856 @default.
• W3173670054 hasAuthorship W3173670054A5046556606 @default.
• W3173670054 hasAuthorship W3173670054A5047248287 @default.
• W3173670054 hasAuthorship W3173670054A5047421296 @default.
• W3173670054 hasAuthorship W3173670054A5051886488 @default.
• W3173670054 hasAuthorship W3173670054A5055748703 @default.
• W3173670054 hasAuthorship W3173670054A5055820345 @default.

• next