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• W3174076304 abstract "Bottom-up micropatterning or nanopatterning can be viewed as the localization of target molecules to the desired area of a surface. A majority of these processes rely on the physical adsorption of ink-like molecules to the paper-like surface, resulting in unstable immobilization of the target molecules owing to their noncovalent linkage to the surface. Herein, successive single nick-sealing facilitated the covalent immobilization of individual DNA molecules at defined positions on a dendron-coated silicon surface using atomic force microscopy. The covalently-patterned ssDNA was visualized when the streptavidin-coated gold nanoparticles bound to the biotinylated DNA. The successive covalent positioning of the target DNA under ambient conditions may facilitate the bottom-up construction of DNA-based durable nanostructures, nanorobots, or memory system." @default.
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• W3174076304 date "2021-06-30" @default.
• W3174076304 modified "2023-09-25" @default.
• W3174076304 title "Covalent Positioning of Single DNA Molecules for Nanopatterning" @default.
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• W3174076304 doi "https://doi.org/10.3390/nano11071725" @default.
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