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• W3174193893 abstract "The aim of this study was to create a comprehensive summary of available mtDNA and Y-chromosome data for Native Americans from North, Central, and South America, including both modern and ancient DNA. To illustrate the usefulness of this dataset we present a broad picture of the genetic variation for both markers across the Americas.We searched PubMed, ResearchGate, Google Scholar for studies about mtDNA or Y-chromosome variation in Native American populations, including geographic, linguistic, ecological (ecoregion), archeological and chronological information. We used AMOVA to estimate the genetic structure associated with language and ecoregion grouping and Mantel tests to evaluate the correlation between genetic and geographic distances.Genetic data were obtained from 321 primary sources, including 22,569 individuals from 298 contemporary populations, and 3628 individuals from 202 archeological populations. MtDNA lineages of probable non-Amerindian origin were rare, in contrast with Y-chromosome lineages. Mantel tests showed a statistically significant correlation for the whole continent considering mtDNA but not the Y-chromosome. Genetic structure between groups was always stronger for mtDNA than for the Y-chromosome.This study summarizes decades of research conducted in Native American populations for both mtDNA and the Y-chromosome. Continental or sub-continental patterns of variation reveal that most of the genetic variation occurs within populations rather than among linguistic or ecoregional groups, and that isolation by distance is barely detectable in most population sets. The genetic structure among groups was always larger for mtDNA than for the Y-chromosome, suggesting between-sex differences in gene flow." @default.
• W3174193893 created "2021-07-05" @default.
• W3174193893 creator A5027961408 @default.
• W3174193893 creator A5071112025 @default.
• W3174193893 date "2021-06-28" @default.
• W3174193893 modified "2023-10-16" @default.
• W3174193893 title "Uniparental genetic markers in Native Americans: A summary of all available data from ancient and contemporary populations" @default.
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• W3174193893 doi "https://doi.org/10.1002/ajpa.24357" @default.
• W3174193893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34184252" @default.
• W3174193893 hasPublicationYear "2021" @default.
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