FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3174212182> ?p ?o ?g. }

• W3174212182 abstract "Abstract Background Bacteriophages are the most abundant biological entity on the planet, and are key components of any ecosystem they are present in. The gut virome is increasingly being implicated in disease states although these studies largely focus on lytic phages in adults. Here we identify prophages from a large infant cohort and investigate their potential functions. Results We identified 10645 vOTUs from 662 metagenomes. No core virome was found: the most prevalent vOTU was identified in 70% of the samples. The most abundant and prevalent group of phages are a novel group closely related to Bacteroides phage Hanky p00’. Functional annotation of this group revealed the presence of genes in the dDTP-L-rhamnose pathway, possibly involved in the production of capsular polysaccharides. We also found an abundance of diversity generating retroelements in the phages. Additionally, paired virome data allowed us to show that the majority of prophages are induced in at least one sample and that this is not affected by the use of antibiotics in the 4 weeks prior to sampling. Conclusions Prophages in the infant gut are largely unique to the individual and not shared. Most of them appear to be induced and so may be key drivers in shaping the bacterial microbiome. The most abundant group of phages are novel, and possess elements that may allow them to maintain differentially susceptible subpopulations of their host bacterium; whilst also containing diversity generating retroelements that could expand their host range. Prophages are important components of the infant gut that may have far reaching influences on the composition and function of the microbiome." @default.
• W3174212182 created "2021-07-05" @default.
• W3174212182 creator A5003075535 @default.
• W3174212182 creator A5006235691 @default.
• W3174212182 creator A5009660232 @default.
• W3174212182 creator A5014990556 @default.
• W3174212182 creator A5031414961 @default.
• W3174212182 creator A5034252850 @default.
• W3174212182 creator A5042196636 @default.
• W3174212182 creator A5051775605 @default.
• W3174212182 creator A5071683172 @default.
• W3174212182 creator A5072773484 @default.
• W3174212182 creator A5075975184 @default.
• W3174212182 date "2021-06-25" @default.
• W3174212182 modified "2023-09-27" @default.
• W3174212182 title "Prophages in the infant gut are largely induced, and may be functionally relevant to their hosts" @default.
• W3174212182 cites W1495239180 @default.
• W3174212182 cites W1528523302 @default.
• W3174212182 cites W1572124882 @default.
• W3174212182 cites W1845989933 @default.
• W3174212182 cites W1904440503 @default.
• W3174212182 cites W1965237471 @default.
• W3174212182 cites W1966783360 @default.
• W3174212182 cites W1967582134 @default.
• W3174212182 cites W1970409435 @default.
• W3174212182 cites W1977151336 @default.
• W3174212182 cites W1981371629 @default.
• W3174212182 cites W1992153121 @default.
• W3174212182 cites W1994759142 @default.
• W3174212182 cites W1996454579 @default.
• W3174212182 cites W2006548437 @default.
• W3174212182 cites W2006995996 @default.
• W3174212182 cites W2016110878 @default.
• W3174212182 cites W2020620061 @default.
• W3174212182 cites W2023506796 @default.
• W3174212182 cites W2024859595 @default.
• W3174212182 cites W2031208736 @default.
• W3174212182 cites W2032699324 @default.
• W3174212182 cites W2052969143 @default.
• W3174212182 cites W2072709771 @default.
• W3174212182 cites W2081319466 @default.
• W3174212182 cites W2089218139 @default.
• W3174212182 cites W2096093282 @default.
• W3174212182 cites W2096205027 @default.
• W3174212182 cites W2099205643 @default.
• W3174212182 cites W2104341696 @default.
• W3174212182 cites W2106844272 @default.
• W3174212182 cites W2108234281 @default.
• W3174212182 cites W2111102241 @default.
• W3174212182 cites W2115985644 @default.
• W3174212182 cites W2121009717 @default.
• W3174212182 cites W2125031539 @default.
• W3174212182 cites W2130546039 @default.
• W3174212182 cites W2135621733 @default.
• W3174212182 cites W2139884694 @default.
• W3174212182 cites W2140660470 @default.
• W3174212182 cites W2145360724 @default.
• W3174212182 cites W2151886256 @default.
• W3174212182 cites W2156125289 @default.
• W3174212182 cites W2161251845 @default.
• W3174212182 cites W2162088497 @default.
• W3174212182 cites W2162228100 @default.
• W3174212182 cites W2165868580 @default.
• W3174212182 cites W2182796952 @default.
• W3174212182 cites W2213612538 @default.
• W3174212182 cites W2271582027 @default.
• W3174212182 cites W2300639547 @default.
• W3174212182 cites W2320903983 @default.
• W3174212182 cites W2321609440 @default.
• W3174212182 cites W2511649068 @default.
• W3174212182 cites W2562882294 @default.
• W3174212182 cites W2638784546 @default.
• W3174212182 cites W2746392566 @default.
• W3174212182 cites W2767759966 @default.
• W3174212182 cites W2782017756 @default.
• W3174212182 cites W2789843538 @default.
• W3174212182 cites W2790367768 @default.
• W3174212182 cites W2806536845 @default.
• W3174212182 cites W2895938591 @default.
• W3174212182 cites W2904384071 @default.
• W3174212182 cites W2943174821 @default.
• W3174212182 cites W2943223175 @default.
• W3174212182 cites W2949452255 @default.
• W3174212182 cites W2949641231 @default.
• W3174212182 cites W2949841808 @default.
• W3174212182 cites W2950060642 @default.
• W3174212182 cites W2950150251 @default.
• W3174212182 cites W2961363344 @default.
• W3174212182 cites W2969443468 @default.
• W3174212182 cites W2997383678 @default.
• W3174212182 cites W2999304916 @default.
• W3174212182 cites W3007341353 @default.
• W3174212182 cites W3010746544 @default.
• W3174212182 cites W3037274972 @default.
• W3174212182 cites W3081166727 @default.
• W3174212182 cites W3081947354 @default.
• W3174212182 cites W3082150690 @default.
• W3174212182 cites W3096218861 @default.
• W3174212182 cites W3108870273 @default.
• W3174212182 cites W3109054969 @default.

• next