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• W3174329078 startingPage "109084" @default.
• W3174329078 abstract "Scaffold degradation regulation has become the key aspects in promoting bone regeneration and reconstruction. In the study, a novel stepwise-degraded PLGA/PCL/HA:Yb/Ho/Zn (PPHZ) scaffold was designed to compare with the fast-degradable PLGA/HA:Yb/Ho/Zn (PLHZ) scaffold to investigate the effects of scaffold degradation regulation on osteogenesis and to trace the scaffold degradation process. Micro-CT reconstruction, confocal fluorescence imaging, and histological sections were used for the analyses of the harvested animal samples, which demonstrated that the degradation regulated stepwise-degraded PPHZ scaffold maintaining higher mechanical strength and longer scaffold integrity is more advantageous for in vivo osteogenesis than the fast-degradable PLHZ scaffold. Meanwhile, the multifunctional HZ particles would help the anti-infection and tracking the distribution during scaffold degradation. The PPHZ scaffold may benefit future repair of anti-infective bone defects and in vivo multimodal tracking." @default.
• W3174329078 created "2021-07-05" @default.
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• W3174329078 date "2021-10-01" @default.
• W3174329078 modified "2023-10-16" @default.
• W3174329078 title "The degradation regulation of 3D printed scaffolds for promotion of osteogenesis and in vivo tracking" @default.
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• W3174329078 doi "https://doi.org/10.1016/j.compositesb.2021.109084" @default.
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