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- W3174362726 endingPage "2022" @default.
- W3174362726 startingPage "2022" @default.
- W3174362726 abstract "Pure bioactive compounds alone can only be exceptionally administered in medical treatment. Usually, drugs are produced as various forms of active compounds and auxiliary substances, combinations assuring the desired healing functions. One of the important drug forms is represented by a combination of active substances and particle-shaped polymer in the nano- or micrometer size range. The review describes recent progress in this field balanced with basic information. After a brief introduction, the paper presents a concise overview of polymers used as components of nano- and microparticle drug carriers. Thereafter, progress in direct synthesis of polymer particles with functional groups is discussed. A section is devoted to formation of particles by self-assembly of homo- and copolymer-bearing functional groups. Special attention is focused on modification of the primary functional groups introduced during particle preparation, including introduction of ligands promoting anchorage of particles onto the chosen living cell types by interactions with specific receptors present in cell membranes. Particular attention is focused on progress in methods suitable for preparation of particles loaded with bioactive substances. The review ends with a brief discussion of the still not answered questions and unsolved problems." @default.
- W3174362726 created "2021-07-05" @default.
- W3174362726 creator A5021632248 @default.
- W3174362726 creator A5028856459 @default.
- W3174362726 creator A5044185656 @default.
- W3174362726 creator A5076056437 @default.
- W3174362726 date "2021-06-21" @default.
- W3174362726 modified "2023-10-16" @default.
- W3174362726 title "Functionalized Particles Designed for Targeted Delivery" @default.
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