Matches in SemOpenAlex for { <https://semopenalex.org/work/W3174365532> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W3174365532 abstract "Fuzhuan tea is a fermented Chinese tea with a unique phytochemical profile which has purported benefits for regulating lipid and glucose metabolism. The mechanism of action by which fuzhuan tea mediates beneficial effects is unknown. Our preliminary studies demonstrate that fuzhuan tea reduced inflammation and liver dysfunction in rats fed a high saturated fat diet (HSFD). Male Wistar rats consumed either control (12% kcal fat) or high saturated fat diets (45% kcal fat with 56% saturated fat), with or without fuzhuan tea supplementation (1400 mg/kg body weight per week) for 8 weeks. Animals given a high saturated fat diet had begun to show increased insulin resistance and markers of inflammation and ER stress in the liver were significantly elevated (p<0.05). In contrast, these effects were attenuated in tea-fed rats consuming HSFD. Furthermore, HSFD resulted in elevated systemic endotoxin levels (1.7 EU/ml compared to 0.7 EU/ml in control diet fed animals) whereas no endotoxin was detected in rats supplemented with fuzhuan tea. Tea-consuming animals showed ~4-fold higher cecal levels of Lactobacillus spp., which modulate intestinal inflammation for improved gut barrier function. In summary, our data suggests that fuzhuan tea may provide protective effects against systemic inflammation and liver injury via effects mediated in the gastrointestinal tract. Funded by: DK072017 CAHS minigrant" @default.
- W3174365532 created "2021-07-05" @default.
- W3174365532 creator A5008125230 @default.
- W3174365532 creator A5027969739 @default.
- W3174365532 creator A5028194262 @default.
- W3174365532 creator A5034128223 @default.
- W3174365532 creator A5038162906 @default.
- W3174365532 creator A5042903397 @default.
- W3174365532 creator A5078836389 @default.
- W3174365532 creator A5080408249 @default.
- W3174365532 date "2013-04-01" @default.
- W3174365532 modified "2023-09-27" @default.
- W3174365532 title "Protective effects of Fuzhuan Tea against high saturated fat diet‐induced inflammation and liver injury in Wistar rats" @default.
- W3174365532 doi "https://doi.org/10.1096/fasebj.27.1_supplement.lb282" @default.
- W3174365532 hasPublicationYear "2013" @default.
- W3174365532 type Work @default.
- W3174365532 sameAs 3174365532 @default.
- W3174365532 citedByCount "0" @default.
- W3174365532 crossrefType "journal-article" @default.
- W3174365532 hasAuthorship W3174365532A5008125230 @default.
- W3174365532 hasAuthorship W3174365532A5027969739 @default.
- W3174365532 hasAuthorship W3174365532A5028194262 @default.
- W3174365532 hasAuthorship W3174365532A5034128223 @default.
- W3174365532 hasAuthorship W3174365532A5038162906 @default.
- W3174365532 hasAuthorship W3174365532A5042903397 @default.
- W3174365532 hasAuthorship W3174365532A5078836389 @default.
- W3174365532 hasAuthorship W3174365532A5080408249 @default.
- W3174365532 hasConcept C126322002 @default.
- W3174365532 hasConcept C185592680 @default.
- W3174365532 hasConcept C2776637226 @default.
- W3174365532 hasConcept C2776914184 @default.
- W3174365532 hasConcept C31903555 @default.
- W3174365532 hasConcept C71924100 @default.
- W3174365532 hasConceptScore W3174365532C126322002 @default.
- W3174365532 hasConceptScore W3174365532C185592680 @default.
- W3174365532 hasConceptScore W3174365532C2776637226 @default.
- W3174365532 hasConceptScore W3174365532C2776914184 @default.
- W3174365532 hasConceptScore W3174365532C31903555 @default.
- W3174365532 hasConceptScore W3174365532C71924100 @default.
- W3174365532 hasIssue "S1" @default.
- W3174365532 hasLocation W31743655321 @default.
- W3174365532 hasOpenAccess W3174365532 @default.
- W3174365532 hasPrimaryLocation W31743655321 @default.
- W3174365532 hasRelatedWork W1808735609 @default.
- W3174365532 hasRelatedWork W2050080970 @default.
- W3174365532 hasRelatedWork W2340310829 @default.
- W3174365532 hasRelatedWork W2354901326 @default.
- W3174365532 hasRelatedWork W2554575616 @default.
- W3174365532 hasRelatedWork W2748952813 @default.
- W3174365532 hasRelatedWork W2899084033 @default.
- W3174365532 hasRelatedWork W4226161835 @default.
- W3174365532 hasRelatedWork W4312093545 @default.
- W3174365532 hasRelatedWork W4323663998 @default.
- W3174365532 hasVolume "27" @default.
- W3174365532 isParatext "false" @default.
- W3174365532 isRetracted "false" @default.
- W3174365532 magId "3174365532" @default.
- W3174365532 workType "article" @default.