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- W3174376909 endingPage "1110" @default.
- W3174376909 startingPage "1092" @default.
- W3174376909 abstract "Abstract Depression is a syndrome characterized by deep sadness and the inhibition of psychic functions, sometimes accompanied by neurovegetative disorders, with symptoms of anxiety almost always present. The disease produces alterations in a variety of neural networks and neurotransmission systems, along with a dysfunction of the hypothalamic-pituitary-adrenal axis, which leads to concomitant alterations in the immunological response. Generally, there is a parallel increase in proinflammatory mediators as well as oxidative and nitrosative damage caused by a reduction of antioxidant defenses. In a previous review, we compiled and examined studies of medicinal plants that had been evaluated in preclinical assays, including existing data on 155 species studied and reported as antidepressants or as sources of active principles for treating this condition. This review will thus limit its focus to the 95 clinical trials found in PubMed among the 670 articles on antidepressant-like medicinal plants. To this end, we have reviewed the publications cited in the Cochrane Database of Systematic Reviews, PubMed, and the Science Citation Index from 2000 to 2020. Our review emphasizes those species that have demonstrated the greatest pharmacological potential when studied for their antidepressant properties in humans through clinical trials. Saffron, turmeric, St. Johnʼs wort, ginkgo, kava, and golden root are the most relevant plants that have provided important evidence for the treatment of depression in clinical trials." @default.
- W3174376909 created "2021-07-05" @default.
- W3174376909 creator A5083177572 @default.
- W3174376909 creator A5087329384 @default.
- W3174376909 date "2021-06-22" @default.
- W3174376909 modified "2023-10-15" @default.
- W3174376909 title "Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials" @default.
- W3174376909 cites W1503361477 @default.
- W3174376909 cites W1509868652 @default.
- W3174376909 cites W1539979186 @default.
- W3174376909 cites W1680724289 @default.
- W3174376909 cites W1835574744 @default.
- W3174376909 cites W1913372371 @default.
- W3174376909 cites W1950423950 @default.
- W3174376909 cites W1973323394 @default.
- W3174376909 cites W1978830885 @default.
- W3174376909 cites W1985438873 @default.
- W3174376909 cites W1985520015 @default.
- W3174376909 cites W1986411631 @default.
- W3174376909 cites W1992144053 @default.
- W3174376909 cites W1993028853 @default.
- W3174376909 cites W1994101653 @default.
- W3174376909 cites W2023750916 @default.
- W3174376909 cites W2032943011 @default.
- W3174376909 cites W2033009851 @default.
- W3174376909 cites W2034040607 @default.
- W3174376909 cites W2035108699 @default.
- W3174376909 cites W2036537363 @default.
- W3174376909 cites W2043304706 @default.
- W3174376909 cites W2045305973 @default.
- W3174376909 cites W2046097935 @default.
- W3174376909 cites W2046134785 @default.
- W3174376909 cites W2048063648 @default.
- W3174376909 cites W2048646100 @default.
- W3174376909 cites W2053491126 @default.
- W3174376909 cites W2064647037 @default.
- W3174376909 cites W2067932965 @default.
- W3174376909 cites W2068655027 @default.
- W3174376909 cites W2073054864 @default.
- W3174376909 cites W2079657721 @default.
- W3174376909 cites W2086986959 @default.
- W3174376909 cites W2089417699 @default.
- W3174376909 cites W2094643645 @default.
- W3174376909 cites W2096622008 @default.
- W3174376909 cites W2097740790 @default.
- W3174376909 cites W2098731039 @default.
- W3174376909 cites W2106623141 @default.
- W3174376909 cites W2108569388 @default.
- W3174376909 cites W2112712523 @default.
- W3174376909 cites W2113576996 @default.
- W3174376909 cites W2117415335 @default.
- W3174376909 cites W2118822483 @default.
- W3174376909 cites W2120115760 @default.
- W3174376909 cites W2122982102 @default.
- W3174376909 cites W2126795224 @default.
- W3174376909 cites W2140144288 @default.
- W3174376909 cites W2141328249 @default.
- W3174376909 cites W2144347730 @default.
- W3174376909 cites W2150470123 @default.
- W3174376909 cites W2150761922 @default.
- W3174376909 cites W2155050526 @default.
- W3174376909 cites W2160340176 @default.
- W3174376909 cites W2162782528 @default.
- W3174376909 cites W2163810480 @default.
- W3174376909 cites W2165393528 @default.
- W3174376909 cites W2174953524 @default.
- W3174376909 cites W2201607793 @default.
- W3174376909 cites W2280064070 @default.
- W3174376909 cites W2280708766 @default.
- W3174376909 cites W2284069661 @default.
- W3174376909 cites W2306848376 @default.
- W3174376909 cites W2315361108 @default.
- W3174376909 cites W2322796880 @default.
- W3174376909 cites W2323433530 @default.
- W3174376909 cites W2324360643 @default.
- W3174376909 cites W2324541548 @default.
- W3174376909 cites W2337056081 @default.
- W3174376909 cites W2399949140 @default.
- W3174376909 cites W2406678754 @default.
- W3174376909 cites W2469512664 @default.
- W3174376909 cites W2473689018 @default.
- W3174376909 cites W2475194264 @default.
- W3174376909 cites W2527907972 @default.
- W3174376909 cites W2547036892 @default.
- W3174376909 cites W2570529618 @default.
- W3174376909 cites W2584697974 @default.
- W3174376909 cites W2589863668 @default.
- W3174376909 cites W2604356374 @default.
- W3174376909 cites W2611710834 @default.
- W3174376909 cites W2752029125 @default.
- W3174376909 cites W2761258032 @default.
- W3174376909 cites W2766083858 @default.
- W3174376909 cites W2767056255 @default.
- W3174376909 cites W2767375938 @default.
- W3174376909 cites W2783008941 @default.
- W3174376909 cites W2783516642 @default.
- W3174376909 cites W2783802379 @default.
- W3174376909 cites W2783816875 @default.