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• W3174381354 endingPage "7119" @default.
• W3174381354 startingPage "7119" @default.
• W3174381354 abstract "Circular RNAs (circRNAs) are an emerging class of regulatory RNAs with a covalently closed-loop structure formed during pre-mRNA splicing. Recent advances in high-throughput RNA sequencing and circRNA-specific computational tools have driven the development of novel approaches to their identification and functional characterization. CircRNAs are stable, developmentally regulated, and show tissue- and cell-type-specific expression across different taxonomic groups. They play a crucial role in regulating various biological processes at post-transcriptional and translational levels. However, the involvement of circRNAs in fish immunity has only recently been recognized. There is also broad evidence in mammals that the timely expression of circRNAs in muscle plays an essential role in growth regulation but our understanding of their expression and function in teleosts is still very limited. Here, we discuss the available knowledge about circRNAs and their role in growth and immunity in vertebrates from a comparative perspective, with emphasis on cultured teleost fish. We expect that the interest in teleost circRNAs will increase substantially soon, and we propose that they may be used as biomarkers for selective breeding of farmed fish, thus contributing to the sustainability of the aquaculture sector." @default.
• W3174381354 created "2021-07-05" @default.
• W3174381354 creator A5014068436 @default.
• W3174381354 creator A5027863333 @default.
• W3174381354 creator A5044718565 @default.
• W3174381354 creator A5077659224 @default.
• W3174381354 date "2021-07-01" @default.
• W3174381354 modified "2023-10-16" @default.
• W3174381354 title "Function of Circular RNAs in Fish and Their Potential Application as Biomarkers" @default.
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