FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3174459871> ?p ?o ?g. }

• W3174459871 endingPage "1017" @default.
• W3174459871 startingPage "1011" @default.
• W3174459871 abstract "Clostridioides difficile is one of the most common nosocomial gastrointestinal pathogens, and recurrence is a problematic issue because approximately 20-30% of patients experience at least one episode of recurrence, even after treatment with a therapeutic drug of choice for C. difficile infection (CDI), such as vancomycin. CDI recurrence has a multifactorial complex mechanism, in which gut microbiota disruption coincident with viable C. difficile spores, is considered the most important factor. The effectiveness of an anti-C. difficile antimicrobial agent against CDI cannot guarantee its inhibitory effect on C. difficile spores and vice versa. However, an antimicrobial agent, such as fidaxomicin, which has a good inhibitory effect on both C. difficile vegetative cells and spores is assumed to not only treat CDI but also prevent its recurrence. Prolonged adherence to the exosporium has been proposed as a possible mechanism of inhibiting spores, and as a result, redesigning anti-C. difficile antimicrobial agents with the ability to adhere to the exosporium may provide another pathway for the development of anti-C. difficile spore agents. For example, vancomycin lacks an inhibitory effect against C. difficile spores, but a vancomycin-loaded spore-targeting iron oxide nanoparticle that selectively binds to C. difficile spores has been developed to successfully delay spore germination. Some new antimicrobial agents in phase II clinical trials, including cadazolid and ridinilazole, have shown exceptional anti-C. difficile and spore-inhibiting effects that can be expected to not only treat CDI but also prevent its recurrence in the future." @default.
• W3174459871 created "2021-07-05" @default.
• W3174459871 creator A5001415903 @default.
• W3174459871 creator A5003684961 @default.
• W3174459871 creator A5026751257 @default.
• W3174459871 creator A5044201260 @default.
• W3174459871 creator A5079674488 @default.
• W3174459871 date "2021-12-01" @default.
• W3174459871 modified "2023-10-18" @default.
• W3174459871 title "Inhibition of spores to prevent the recurrence of Clostridioides difficile infection - A possibility or an improbability?" @default.
• W3174459871 cites W2010470461 @default.
• W3174459871 cites W2035313996 @default.
• W3174459871 cites W2050477232 @default.
• W3174459871 cites W2055452596 @default.
• W3174459871 cites W2065777365 @default.
• W3174459871 cites W2068491817 @default.
• W3174459871 cites W2081161743 @default.
• W3174459871 cites W2096284531 @default.
• W3174459871 cites W2097297514 @default.
• W3174459871 cites W2098455823 @default.
• W3174459871 cites W2102219089 @default.
• W3174459871 cites W2106993534 @default.
• W3174459871 cites W2112404034 @default.
• W3174459871 cites W2113335688 @default.
• W3174459871 cites W2113556993 @default.
• W3174459871 cites W2114314510 @default.
• W3174459871 cites W2116355501 @default.
• W3174459871 cites W2118595097 @default.
• W3174459871 cites W2119031245 @default.
• W3174459871 cites W2124954246 @default.
• W3174459871 cites W2132537147 @default.
• W3174459871 cites W2141900053 @default.
• W3174459871 cites W2149215043 @default.
• W3174459871 cites W2160661831 @default.
• W3174459871 cites W2165954112 @default.
• W3174459871 cites W2168453790 @default.
• W3174459871 cites W2169854262 @default.
• W3174459871 cites W2170699724 @default.
• W3174459871 cites W2175167624 @default.
• W3174459871 cites W2286053779 @default.
• W3174459871 cites W2507523231 @default.
• W3174459871 cites W2510650522 @default.
• W3174459871 cites W2608048982 @default.
• W3174459871 cites W2740742338 @default.
• W3174459871 cites W2743500738 @default.
• W3174459871 cites W2743960433 @default.
• W3174459871 cites W2762981429 @default.
• W3174459871 cites W2771567848 @default.
• W3174459871 cites W2776667275 @default.
• W3174459871 cites W2791617388 @default.
• W3174459871 cites W2791974907 @default.
• W3174459871 cites W2802681502 @default.
• W3174459871 cites W2804831184 @default.
• W3174459871 cites W2888738388 @default.
• W3174459871 cites W2889373630 @default.
• W3174459871 cites W2890578491 @default.
• W3174459871 cites W2914079964 @default.
• W3174459871 cites W2944035856 @default.
• W3174459871 cites W2964558649 @default.
• W3174459871 cites W2965028233 @default.
• W3174459871 cites W2965138893 @default.
• W3174459871 cites W2975579232 @default.
• W3174459871 cites W2977938678 @default.
• W3174459871 cites W3006633129 @default.
• W3174459871 cites W3011089780 @default.
• W3174459871 cites W3038054500 @default.
• W3174459871 cites W3122975819 @default.
• W3174459871 cites W3132239220 @default.
• W3174459871 cites W4251404301 @default.
• W3174459871 doi "https://doi.org/10.1016/j.jmii.2021.06.002" @default.
• W3174459871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34229970" @default.
• W3174459871 hasPublicationYear "2021" @default.
• W3174459871 type Work @default.
• W3174459871 sameAs 3174459871 @default.
• W3174459871 citedByCount "8" @default.
• W3174459871 countsByYear W31744598712022 @default.
• W3174459871 countsByYear W31744598712023 @default.
• W3174459871 crossrefType "journal-article" @default.
• W3174459871 hasAuthorship W3174459871A5001415903 @default.
• W3174459871 hasAuthorship W3174459871A5003684961 @default.
• W3174459871 hasAuthorship W3174459871A5026751257 @default.
• W3174459871 hasAuthorship W3174459871A5044201260 @default.
• W3174459871 hasAuthorship W3174459871A5079674488 @default.
• W3174459871 hasBestOaLocation W31744598711 @default.
• W3174459871 hasConcept C174618031 @default.
• W3174459871 hasConcept C2778980435 @default.
• W3174459871 hasConcept C2779489039 @default.
• W3174459871 hasConcept C2781342628 @default.
• W3174459871 hasConcept C2910067853 @default.
• W3174459871 hasConcept C2994496256 @default.
• W3174459871 hasConcept C4937899 @default.
• W3174459871 hasConcept C501593827 @default.
• W3174459871 hasConcept C523546767 @default.
• W3174459871 hasConcept C54355233 @default.
• W3174459871 hasConcept C71924100 @default.
• W3174459871 hasConcept C86803240 @default.
• W3174459871 hasConcept C89423630 @default.
• W3174459871 hasConceptScore W3174459871C174618031 @default.

• next