FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3174505835> ?p ?o ?g. }

• W3174505835 endingPage "347" @default.
• W3174505835 startingPage "334" @default.
• W3174505835 abstract "Introduction: Three prominent resting-state networks (rsNW) (default mode network [DMN], salience network [SN], and central executive network [CEN]) are recognized for their important role in several neuropsychiatric conditions. However, our understanding of their relevance in terms of cognition remains insufficient. Materials and Methods: In response, this study aims at investigating the patterns of different network properties (resting-state activity [RSA] and short- and long-range functional connectivity [FC]) in these three core rsNWs, as well as the dynamics of age-associated changes and their relation to cognitive performance in a sample of healthy controls (N = 74) covering a large age span (20-79 years). Using a whole-network based approach, three measures were calculated from the functional magnetic resonance imaging (fMRI) data: amplitude of low-frequency fluctuations (ALFF), regional homogeneity (ReHo), and degree of network centrality (DC). The cognitive test battery covered the following domains: memory, executive functioning, processing speed, attention, and visual perception. Results: For all three fMRI measures (ALFF, ReHo, and DC), the highest values of spontaneous brain activity (ALFF), short- and long-range connectivity (ReHo, DC) were observed in the DMN and the lowest in the SN. Significant age-associated decrease was observed in the DMN for ALFF and DC, and in the SN for ALFF and ReHo. Significant negative partial correlations were observed for working memory and ALFF in all three networks, as well as for additional cognitive parameters and ALFF in CEN. Discussion: Our results show that higher RSA in the three core rsNWs may have an unfavorable effect on cognition. Conversely, the pattern of network properties in healthy subjects included low RSA and FC in the SN. This complements previous research related to the three core rsNW and shows that the chosen approach can provide additional insight into their function. Impact statement Using a whole network-based approach, our study characterizes the normal patterns (including resting-state activity [RSA], short- and long-range functional connectivity [FC]) of three prominent resting-state networks (rsNW) within the context of age-dependent changes and explores their relevance for different cognitive domains. Our results revealed a pattern with low RSA and FC in the salience network in healthy volunteers, whereas higher RSA, particularly in the central executive network, seemed to have a negative effect on cognition. These results increase the knowledge about the three core rsNWs and the understanding about their relevance for cognition." @default.
• W3174505835 created "2021-07-05" @default.
• W3174505835 creator A5012215491 @default.
• W3174505835 creator A5014981133 @default.
• W3174505835 creator A5043619387 @default.
• W3174505835 creator A5049811654 @default.
• W3174505835 creator A5052251830 @default.
• W3174505835 creator A5081914732 @default.
• W3174505835 creator A5084753515 @default.
• W3174505835 date "2022-05-01" @default.
• W3174505835 modified "2023-10-18" @default.
• W3174505835 title "Connectivity Patterns in the Core Resting-State Networks and Their Influence on Cognition" @default.
• W3174505835 cites W1552179169 @default.
• W3174505835 cites W1966805834 @default.
• W3174505835 cites W1967628934 @default.
• W3174505835 cites W1969845534 @default.
• W3174505835 cites W1970508569 @default.
• W3174505835 cites W1972083454 @default.
• W3174505835 cites W1978408307 @default.
• W3174505835 cites W1981628905 @default.
• W3174505835 cites W1984111197 @default.
• W3174505835 cites W1989978280 @default.
• W3174505835 cites W2000555003 @default.
• W3174505835 cites W2001971205 @default.
• W3174505835 cites W2004371763 @default.
• W3174505835 cites W2005933475 @default.
• W3174505835 cites W2007213925 @default.
• W3174505835 cites W2008607322 @default.
• W3174505835 cites W2009494091 @default.
• W3174505835 cites W2017658548 @default.
• W3174505835 cites W2019335829 @default.
• W3174505835 cites W2025320437 @default.
• W3174505835 cites W2031594486 @default.
• W3174505835 cites W2035678379 @default.
• W3174505835 cites W2047342826 @default.
• W3174505835 cites W2047959911 @default.
• W3174505835 cites W2055862036 @default.
• W3174505835 cites W2063435176 @default.
• W3174505835 cites W2070450901 @default.
• W3174505835 cites W2077716286 @default.
• W3174505835 cites W2078563124 @default.
• W3174505835 cites W2084709418 @default.
• W3174505835 cites W2090172100 @default.
• W3174505835 cites W2091465235 @default.
• W3174505835 cites W2097982135 @default.
• W3174505835 cites W2100235615 @default.
• W3174505835 cites W2101219946 @default.
• W3174505835 cites W2104811988 @default.
• W3174505835 cites W2105558714 @default.
• W3174505835 cites W2106990053 @default.
• W3174505835 cites W2115012618 @default.
• W3174505835 cites W2116658855 @default.
• W3174505835 cites W2119618432 @default.
• W3174505835 cites W2123330196 @default.
• W3174505835 cites W2124490687 @default.
• W3174505835 cites W2126650951 @default.
• W3174505835 cites W2126817549 @default.
• W3174505835 cites W2129624700 @default.
• W3174505835 cites W2132827635 @default.
• W3174505835 cites W2133173194 @default.
• W3174505835 cites W2133903921 @default.
• W3174505835 cites W2136022845 @default.
• W3174505835 cites W2136148200 @default.
• W3174505835 cites W2136199096 @default.
• W3174505835 cites W2139289770 @default.
• W3174505835 cites W2147546041 @default.
• W3174505835 cites W2149240439 @default.
• W3174505835 cites W2150449074 @default.
• W3174505835 cites W2150456075 @default.
• W3174505835 cites W2156152318 @default.
• W3174505835 cites W2159929956 @default.
• W3174505835 cites W2161502085 @default.
• W3174505835 cites W2163005465 @default.
• W3174505835 cites W2298055498 @default.
• W3174505835 cites W2337323496 @default.
• W3174505835 cites W2339877204 @default.
• W3174505835 cites W2409284958 @default.
• W3174505835 cites W2512349860 @default.
• W3174505835 cites W2514368494 @default.
• W3174505835 cites W2526350827 @default.
• W3174505835 cites W2538853854 @default.
• W3174505835 cites W2551764080 @default.
• W3174505835 cites W2560693837 @default.
• W3174505835 cites W2587192888 @default.
• W3174505835 cites W2592440757 @default.
• W3174505835 cites W2593371527 @default.
• W3174505835 cites W2605186574 @default.
• W3174505835 cites W2611393551 @default.
• W3174505835 cites W2611420883 @default.
• W3174505835 cites W2616873190 @default.
• W3174505835 cites W2619299539 @default.
• W3174505835 cites W2737966895 @default.
• W3174505835 cites W2791832527 @default.
• W3174505835 cites W2794423579 @default.
• W3174505835 cites W2795262405 @default.
• W3174505835 cites W2810216104 @default.
• W3174505835 cites W2884319195 @default.
• W3174505835 cites W2887070634 @default.

• next