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- W3174574167 abstract "We have reported that the highest ratios of O2 uptake and CO2 output to ventilation (VO2/VE and VCO2/VE) occur during moderate rather than maximal exercise and that lower ratios better predict early cardiac death than lower peak VO2 or anaerobic threshold values. Therefore we postulated that plotting simultaneous VO2/VE-vs-VCO2/VE values of incremental exercise studies against each other on X-Y axes would give an easy-to-understand single display that might quantify cardiovascular performance exceptionally well. Plots of 90-s rolling averages of VO2/VE-vs-VCO2/VE were optimal. The diagonal oval racetrack patterns of VO2/VE-vs-VCO2/VE in normal subjects were distinctive. In over 300 normal subjects, reference formulas in mL (STPD)/L (BTPS) for highest VO2/VE = 42.2 – 0.189yrs +0.036cm less 3.0 for women and for highest VCO2/VE = 38.9 – 0.155yrs + 0.038cm less 1.9 for women. The patterns and highest values for patients with left or right heart failure were also examined. Patients with more severe heart failure had lower VO2/VE-vs-VCO2/VE values at rest with exercise values moving in an abnormal direction. We conclude that highest VO2/VE and VCO2/VE values, elicited without maximal exercise, are important parameters. Further, plots of VO2/VE-vs-VCO2/VE yield distinctive patterns that alone well assess cardiac performance and disease. No government, industry, or institutional support." @default.
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- W3174574167 date "2012-04-01" @default.
- W3174574167 modified "2023-09-24" @default.
- W3174574167 title "A useful, innovative, and visual method to quantify fitness and heart failure" @default.
- W3174574167 doi "https://doi.org/10.1096/fasebj.26.1_supplement.1138.49" @default.
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