Matches in SemOpenAlex for { <https://semopenalex.org/work/W3174609537> ?p ?o ?g. }
- W3174609537 endingPage "122" @default.
- W3174609537 startingPage "115" @default.
- W3174609537 abstract "Pituitary adenoma (PA) accounts for 10-15% of all intracranial neoplasms. Despite their benign nature, PA often shows invasive growth. MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are a class of non-coding RNAs that play important roles in PA initiation and progression.The aim of this study was to find specific profiles of miR-200a and long non-coding RNA (lncRNA) antisense non-coding RNA in the INK4 locus (ANRIL) in PA based on a comparative study using Real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) analyses of tumor tissue and plasma.Plasma and PA tissue samples were obtained from two groups of included patients (15 invasive and 15 non-invasive PA). In addition, plasma samples from patients with invasive PA have collected pre- and post-operation. Plasma and tissue samples subjected to qRT-PCR analyses for the expression levels of miR-200a and lncRNA ANRIL.The expression levels of miR-200a and lncRNA ANRIL were increased in tissue samples patients with invasive PA than in the patients with non-invasive PA. In addition, the expression levels of circulating miR-200a and lncRNA ANRIL were increased in patients with invasive PA than in patients with non-invasive PA in the pre-operation period. However, the expression level of plasma circulating miR-200a and lncRNA ANRIL was decreased in patients with invasive PA in the post-operation period. Our results depicted a miR-200a and lncRNA ANRIL expression in tissue and plasma samples in the patients with invasive PA. In addition, Receiver Operating Characteristic (ROC) curve was used to evaluate the diagnostic value of these circulating miR-200a and lncRNA ANRIL.The expression of these tumor-associated ncRNAs has been elevated in the PAs. Therefore, miR-200a and lncRNA ANRIL represents as biomarkers for diagnosis and potential targets for novel invasive PA treatment strategies." @default.
- W3174609537 created "2021-07-05" @default.
- W3174609537 creator A5012293083 @default.
- W3174609537 creator A5035036359 @default.
- W3174609537 creator A5035122818 @default.
- W3174609537 creator A5045549546 @default.
- W3174609537 creator A5054303514 @default.
- W3174609537 creator A5066515223 @default.
- W3174609537 creator A5069375106 @default.
- W3174609537 creator A5072765154 @default.
- W3174609537 creator A5082273591 @default.
- W3174609537 date "2021-09-01" @default.
- W3174609537 modified "2023-10-15" @default.
- W3174609537 title "Differential non-coding RNAs expression profiles of invasive and non-invasive pituitary adenomas" @default.
- W3174609537 cites W1831343844 @default.
- W3174609537 cites W2016441119 @default.
- W3174609537 cites W2099202255 @default.
- W3174609537 cites W2132304416 @default.
- W3174609537 cites W2143207688 @default.
- W3174609537 cites W2158824170 @default.
- W3174609537 cites W2476583535 @default.
- W3174609537 cites W2543495975 @default.
- W3174609537 cites W2595235288 @default.
- W3174609537 cites W2616387549 @default.
- W3174609537 cites W2751729201 @default.
- W3174609537 cites W2767004972 @default.
- W3174609537 cites W2793307789 @default.
- W3174609537 cites W2801430015 @default.
- W3174609537 cites W2803222773 @default.
- W3174609537 cites W2884904939 @default.
- W3174609537 cites W2891073452 @default.
- W3174609537 cites W2899178572 @default.
- W3174609537 cites W2939321141 @default.
- W3174609537 cites W2946643024 @default.
- W3174609537 cites W2955143464 @default.
- W3174609537 cites W2961534630 @default.
- W3174609537 cites W2966300343 @default.
- W3174609537 cites W2967007608 @default.
- W3174609537 cites W2972903734 @default.
- W3174609537 cites W2979143022 @default.
- W3174609537 cites W2980778519 @default.
- W3174609537 cites W2980848969 @default.
- W3174609537 cites W2982711111 @default.
- W3174609537 cites W2986484251 @default.
- W3174609537 cites W2988643833 @default.
- W3174609537 cites W2990288178 @default.
- W3174609537 cites W2991128085 @default.
- W3174609537 cites W2991719783 @default.
- W3174609537 cites W3026447802 @default.
- W3174609537 cites W3087113615 @default.
- W3174609537 cites W3090576630 @default.
- W3174609537 cites W3093206413 @default.
- W3174609537 cites W4247544731 @default.
- W3174609537 doi "https://doi.org/10.1016/j.ncrna.2021.06.004" @default.
- W3174609537 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8283030" @default.
- W3174609537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34322647" @default.
- W3174609537 hasPublicationYear "2021" @default.
- W3174609537 type Work @default.
- W3174609537 sameAs 3174609537 @default.
- W3174609537 citedByCount "24" @default.
- W3174609537 countsByYear W31746095372021 @default.
- W3174609537 countsByYear W31746095372022 @default.
- W3174609537 countsByYear W31746095372023 @default.
- W3174609537 crossrefType "journal-article" @default.
- W3174609537 hasAuthorship W3174609537A5012293083 @default.
- W3174609537 hasAuthorship W3174609537A5035036359 @default.
- W3174609537 hasAuthorship W3174609537A5035122818 @default.
- W3174609537 hasAuthorship W3174609537A5045549546 @default.
- W3174609537 hasAuthorship W3174609537A5054303514 @default.
- W3174609537 hasAuthorship W3174609537A5066515223 @default.
- W3174609537 hasAuthorship W3174609537A5069375106 @default.
- W3174609537 hasAuthorship W3174609537A5072765154 @default.
- W3174609537 hasAuthorship W3174609537A5082273591 @default.
- W3174609537 hasBestOaLocation W31746095371 @default.
- W3174609537 hasConcept C104317684 @default.
- W3174609537 hasConcept C145059251 @default.
- W3174609537 hasConcept C48023723 @default.
- W3174609537 hasConcept C502942594 @default.
- W3174609537 hasConcept C54355233 @default.
- W3174609537 hasConcept C62203573 @default.
- W3174609537 hasConcept C67705224 @default.
- W3174609537 hasConcept C86803240 @default.
- W3174609537 hasConceptScore W3174609537C104317684 @default.
- W3174609537 hasConceptScore W3174609537C145059251 @default.
- W3174609537 hasConceptScore W3174609537C48023723 @default.
- W3174609537 hasConceptScore W3174609537C502942594 @default.
- W3174609537 hasConceptScore W3174609537C54355233 @default.
- W3174609537 hasConceptScore W3174609537C62203573 @default.
- W3174609537 hasConceptScore W3174609537C67705224 @default.
- W3174609537 hasConceptScore W3174609537C86803240 @default.
- W3174609537 hasFunder F4320321001 @default.
- W3174609537 hasFunder F4320321079 @default.
- W3174609537 hasIssue "3" @default.
- W3174609537 hasLocation W31746095371 @default.
- W3174609537 hasLocation W31746095372 @default.
- W3174609537 hasLocation W31746095373 @default.
- W3174609537 hasOpenAccess W3174609537 @default.
- W3174609537 hasPrimaryLocation W31746095371 @default.