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- W3174692433 abstract "Obesity and colon health is a growing medical problem in the U.S. Previous studies have shown independent effectiveness of resistant starch (RS) and high protein (HP) diets in decreasing body fat. HP diets have been shown to reduce food intake by altering brain neuropeptides. RS may produce this effect through mechanisms related to colonic fermentation that also improves colon health. The objective of this study was to determine whether there are additive effects of RS (20%) and high protein (40 %) on the reduction of fat accumulation. Forty female rats were fed control diets for a 4 week free feeding period. Rats were then stratified by weight and placed in 4 diet treatment groups (n=10): HP, RS, RS/HP and control. They were meal fed for a 2 week restricted feeding period followed by an 8 week free feeding rebound period. Analysis was a 2x2 factorial followed by LSD mean comparisons (p<0.05). HP/RS showed a significant reduction in mesenteric and % total dissected fat. There were synergistic interactions between RS and HP as the RS/HP group had the lowest pH and greatest cecal contents which are indicators of fermentation. This combination may reduce body fat levels and benefit the health of the colon. Funded by the LSU AgCenter." @default.
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- W3174692433 date "2009-04-01" @default.
- W3174692433 modified "2023-09-27" @default.
- W3174692433 title "High protein and resistant starch have a synergistic effect on reducing body fat levels and increasing fermentation in rats" @default.
- W3174692433 doi "https://doi.org/10.1096/fasebj.23.1_supplement.563.6" @default.
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