Matches in SemOpenAlex for { <https://semopenalex.org/work/W3174894006> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W3174894006 abstract "The interactions between the autonomic nervous system (ANS), intrinsic systems (e.g., endocrine), and internal pacemaker mechanisms govern short (milliseconds-seconds)- and long (seconds-minutes)-range heart rate variability (HRV). However, there is a debate regarding the identity of the mechanism underlying HRV on each time scale. We aim to design a general method that accurately differentiates between the relative contribution of the ANS and pacemaker mechanisms to HRV in various mammals, without the need for drug perturbations or organ isolation. Additionally, we aim to explore the universality of the relative contribution of the ANS and pacemaker system of different mammals.This work explored short- and long-range HRVs using published ECG data from dogs, rabbits, and mice. To isolate the effects of ANS on HRV, ECG segments recorded before and after ANS-blockade were compared.Differentiation of the ANS from extrinsic and intrinsic pacemaker mechanisms was successfully achieved. In dogs, the internal pacemaker mechanisms were the main contributors to long-range and the ANS to short-range HRV. In rabbits and mice, the ANS and the internal pacemaker mechanisms affected both time scales, and anesthesia changed the relative contribution of the pacemaker mechanism to short- and long-range HRVs. In mice, the extrinsic mechanisms affected long-range HRV, while their effect was negligible in rabbits.We offer a novel approach to determine the relative contributions of ANS and extrinsic and intrinsic pacemaker mechanisms to HRV and highlight the importance of selecting mammalian research models with HRV mechanisms representative of the target species of interest." @default.
- W3174894006 created "2021-07-05" @default.
- W3174894006 creator A5020412303 @default.
- W3174894006 creator A5045139283 @default.
- W3174894006 creator A5049573849 @default.
- W3174894006 creator A5083936087 @default.
- W3174894006 creator A5086863977 @default.
- W3174894006 date "2021-06-30" @default.
- W3174894006 modified "2023-10-17" @default.
- W3174894006 title "Opening the Schrödinger Box: Short- and Long-Range Mammalian Heart Rate Variability" @default.
- W3174894006 cites W1862394037 @default.
- W3174894006 cites W1989555285 @default.
- W3174894006 cites W2002634573 @default.
- W3174894006 cites W2024673434 @default.
- W3174894006 cites W2033168463 @default.
- W3174894006 cites W2036789507 @default.
- W3174894006 cites W2063370166 @default.
- W3174894006 cites W2081486315 @default.
- W3174894006 cites W2102423296 @default.
- W3174894006 cites W2112400936 @default.
- W3174894006 cites W2121383959 @default.
- W3174894006 cites W2122463700 @default.
- W3174894006 cites W2130534913 @default.
- W3174894006 cites W2149132899 @default.
- W3174894006 cites W2150707525 @default.
- W3174894006 cites W2162800060 @default.
- W3174894006 cites W2163798869 @default.
- W3174894006 cites W2165636960 @default.
- W3174894006 cites W2383759838 @default.
- W3174894006 cites W2808679697 @default.
- W3174894006 cites W2866922461 @default.
- W3174894006 cites W2895333514 @default.
- W3174894006 cites W2950126964 @default.
- W3174894006 cites W2990869740 @default.
- W3174894006 cites W3036898299 @default.
- W3174894006 cites W3132448209 @default.
- W3174894006 cites W4298059290 @default.
- W3174894006 doi "https://doi.org/10.3389/fphys.2021.665709" @default.
- W3174894006 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8278020" @default.
- W3174894006 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34276396" @default.
- W3174894006 hasPublicationYear "2021" @default.
- W3174894006 type Work @default.
- W3174894006 sameAs 3174894006 @default.
- W3174894006 citedByCount "1" @default.
- W3174894006 countsByYear W31748940062022 @default.
- W3174894006 crossrefType "journal-article" @default.
- W3174894006 hasAuthorship W3174894006A5020412303 @default.
- W3174894006 hasAuthorship W3174894006A5045139283 @default.
- W3174894006 hasAuthorship W3174894006A5049573849 @default.
- W3174894006 hasAuthorship W3174894006A5083936087 @default.
- W3174894006 hasAuthorship W3174894006A5086863977 @default.
- W3174894006 hasBestOaLocation W31748940061 @default.
- W3174894006 hasConcept C121332964 @default.
- W3174894006 hasConcept C126322002 @default.
- W3174894006 hasConcept C2777372248 @default.
- W3174894006 hasConcept C2777953023 @default.
- W3174894006 hasConcept C62520636 @default.
- W3174894006 hasConcept C71635504 @default.
- W3174894006 hasConcept C71924100 @default.
- W3174894006 hasConcept C84393581 @default.
- W3174894006 hasConcept C86803240 @default.
- W3174894006 hasConcept C89611455 @default.
- W3174894006 hasConceptScore W3174894006C121332964 @default.
- W3174894006 hasConceptScore W3174894006C126322002 @default.
- W3174894006 hasConceptScore W3174894006C2777372248 @default.
- W3174894006 hasConceptScore W3174894006C2777953023 @default.
- W3174894006 hasConceptScore W3174894006C62520636 @default.
- W3174894006 hasConceptScore W3174894006C71635504 @default.
- W3174894006 hasConceptScore W3174894006C71924100 @default.
- W3174894006 hasConceptScore W3174894006C84393581 @default.
- W3174894006 hasConceptScore W3174894006C86803240 @default.
- W3174894006 hasConceptScore W3174894006C89611455 @default.
- W3174894006 hasFunder F4320322252 @default.
- W3174894006 hasLocation W31748940061 @default.
- W3174894006 hasLocation W31748940062 @default.
- W3174894006 hasLocation W31748940063 @default.
- W3174894006 hasOpenAccess W3174894006 @default.
- W3174894006 hasPrimaryLocation W31748940061 @default.
- W3174894006 hasRelatedWork W1965419675 @default.
- W3174894006 hasRelatedWork W2001524389 @default.
- W3174894006 hasRelatedWork W2041478974 @default.
- W3174894006 hasRelatedWork W2072521651 @default.
- W3174894006 hasRelatedWork W2166124410 @default.
- W3174894006 hasRelatedWork W2182975669 @default.
- W3174894006 hasRelatedWork W2384377368 @default.
- W3174894006 hasRelatedWork W2501692008 @default.
- W3174894006 hasRelatedWork W3000240560 @default.
- W3174894006 hasRelatedWork W3047291960 @default.
- W3174894006 hasVolume "12" @default.
- W3174894006 isParatext "false" @default.
- W3174894006 isRetracted "false" @default.
- W3174894006 magId "3174894006" @default.
- W3174894006 workType "article" @default.