FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3174930574> ?p ?o ?g. }

• W3174930574 abstract "Docetaxel-based chemotherapy, as the first-line treatment for metastatic castration-resistant prostate cancer (mCRPC), has succeeded in helping quite a number of patients to improve quality of life and prolong survival time. However, almost half of mCRPC patients are not sensitive to docetaxel chemotherapy initially. This study aimed to establish models to predict sensitivity to docetaxel chemotherapy in patients with mCRPC by using serum surface-enhanced Raman spectroscopy (SERS). A total of 32 mCPRC patients who underwent docetaxel chemotherapy at our center from July 2016 to March 2018 were included in this study. Patients were dichotomized in prostate-specific antigen (PSA) response group ([Formula: see text]) versus PSA failure group ([Formula: see text]) according to the response to docetaxel. In total 64 matched spectra from 32 mCRPC patients were obtained by using SERS of serum at baseline ([Formula: see text]0) and after 1 cycle of docetaxel chemotherapy ([Formula: see text]1). Comparing Raman peaks of serum samples at baseline ([Formula: see text]0) between two groups, significant differences revealed at the peaks of 638, 810, 890 ([Formula: see text]) and 1136[Formula: see text]cm[Formula: see text] ([Formula: see text]). The prediction models of peak 1363[Formula: see text]cm[Formula: see text] and principal component analysis and linear discriminant analysis (PCA–LDA) based on Raman data were established, respectively. The sensitivity and specificity of the prediction models were 71%, 80% and 69%, 78% through the way of leave-one-out cross-validation. According to the results of five-cross-validation, the PCA–LDA model revealed an accuracy of 0.73 and AUC of 0.83." @default.
• W3174930574 created "2021-07-05" @default.
• W3174930574 creator A5009027431 @default.
• W3174930574 creator A5013129340 @default.
• W3174930574 creator A5016243869 @default.
• W3174930574 creator A5016942534 @default.
• W3174930574 creator A5050531186 @default.
• W3174930574 creator A5057863237 @default.
• W3174930574 creator A5072195107 @default.
• W3174930574 creator A5077353181 @default.
• W3174930574 creator A5089344831 @default.
• W3174930574 date "2021-06-23" @default.
• W3174930574 modified "2023-09-30" @default.
• W3174930574 title "Surface-enhanced Raman spectroscopy of serum predicts sensitivity to docetaxel-based chemotherapy in patients with metastatic castration-resistant prostate cancer" @default.
• W3174930574 cites W1091392161 @default.
• W3174930574 cites W1119887047 @default.
• W3174930574 cites W1965554123 @default.
• W3174930574 cites W1968871412 @default.
• W3174930574 cites W1982906652 @default.
• W3174930574 cites W2004973733 @default.
• W3174930574 cites W2005958584 @default.
• W3174930574 cites W2015647052 @default.
• W3174930574 cites W2036449946 @default.
• W3174930574 cites W2046072267 @default.
• W3174930574 cites W2058484579 @default.
• W3174930574 cites W2072752349 @default.
• W3174930574 cites W2080439368 @default.
• W3174930574 cites W2088904434 @default.
• W3174930574 cites W2094938672 @default.
• W3174930574 cites W2120292596 @default.
• W3174930574 cites W2148998801 @default.
• W3174930574 cites W2166374791 @default.
• W3174930574 cites W2261541998 @default.
• W3174930574 cites W2278392405 @default.
• W3174930574 cites W2289244923 @default.
• W3174930574 cites W2549862740 @default.
• W3174930574 cites W2563212520 @default.
• W3174930574 cites W2739973633 @default.
• W3174930574 cites W2888953771 @default.
• W3174930574 cites W2901320017 @default.
• W3174930574 cites W2909492774 @default.
• W3174930574 cites W2999417355 @default.
• W3174930574 cites W4238768614 @default.
• W3174930574 doi "https://doi.org/10.1142/s1793545821410066" @default.
• W3174930574 hasPublicationYear "2021" @default.
• W3174930574 type Work @default.
• W3174930574 sameAs 3174930574 @default.
• W3174930574 citedByCount "8" @default.
• W3174930574 countsByYear W31749305742021 @default.
• W3174930574 countsByYear W31749305742022 @default.
• W3174930574 countsByYear W31749305742023 @default.
• W3174930574 crossrefType "journal-article" @default.
• W3174930574 hasAuthorship W3174930574A5009027431 @default.
• W3174930574 hasAuthorship W3174930574A5013129340 @default.
• W3174930574 hasAuthorship W3174930574A5016243869 @default.
• W3174930574 hasAuthorship W3174930574A5016942534 @default.
• W3174930574 hasAuthorship W3174930574A5050531186 @default.
• W3174930574 hasAuthorship W3174930574A5057863237 @default.
• W3174930574 hasAuthorship W3174930574A5072195107 @default.
• W3174930574 hasAuthorship W3174930574A5077353181 @default.
• W3174930574 hasAuthorship W3174930574A5089344831 @default.
• W3174930574 hasBestOaLocation W31749305741 @default.
• W3174930574 hasConcept C120665830 @default.
• W3174930574 hasConcept C121332964 @default.
• W3174930574 hasConcept C121608353 @default.
• W3174930574 hasConcept C126322002 @default.
• W3174930574 hasConcept C126894567 @default.
• W3174930574 hasConcept C143998085 @default.
• W3174930574 hasConcept C2776694085 @default.
• W3174930574 hasConcept C2780192828 @default.
• W3174930574 hasConcept C2781190966 @default.
• W3174930574 hasConcept C2781406297 @default.
• W3174930574 hasConcept C40003534 @default.
• W3174930574 hasConcept C71924100 @default.
• W3174930574 hasConceptScore W3174930574C120665830 @default.
• W3174930574 hasConceptScore W3174930574C121332964 @default.
• W3174930574 hasConceptScore W3174930574C121608353 @default.
• W3174930574 hasConceptScore W3174930574C126322002 @default.
• W3174930574 hasConceptScore W3174930574C126894567 @default.
• W3174930574 hasConceptScore W3174930574C143998085 @default.
• W3174930574 hasConceptScore W3174930574C2776694085 @default.
• W3174930574 hasConceptScore W3174930574C2780192828 @default.
• W3174930574 hasConceptScore W3174930574C2781190966 @default.
• W3174930574 hasConceptScore W3174930574C2781406297 @default.
• W3174930574 hasConceptScore W3174930574C40003534 @default.
• W3174930574 hasConceptScore W3174930574C71924100 @default.
• W3174930574 hasFunder F4320326252 @default.
• W3174930574 hasFunder F4320335581 @default.
• W3174930574 hasIssue "04" @default.
• W3174930574 hasLocation W31749305741 @default.
• W3174930574 hasOpenAccess W3174930574 @default.
• W3174930574 hasPrimaryLocation W31749305741 @default.
• W3174930574 hasRelatedWork W2010765098 @default.
• W3174930574 hasRelatedWork W2060708716 @default.
• W3174930574 hasRelatedWork W2080820783 @default.
• W3174930574 hasRelatedWork W2094570582 @default.
• W3174930574 hasRelatedWork W2135620818 @default.
• W3174930574 hasRelatedWork W2407641156 @default.
• W3174930574 hasRelatedWork W2568045406 @default.
• W3174930574 hasRelatedWork W2588988563 @default.

• next