Matches in SemOpenAlex for { <https://semopenalex.org/work/W3174948003> ?p ?o ?g. }
- W3174948003 endingPage "100742" @default.
- W3174948003 startingPage "100742" @default.
- W3174948003 abstract "A new series of aryl chalcone incorporated thieno[2,3- d ]thiazoles ( 10a-j ) have been designed and synthesized and their structures were confirmed by analytical data. Further, these derivatives were screened for their anticancer activity towards four human cancer cell lines such as prostate cancer (PC3), lung cancer (A549), breast cancer (MCF-7) and ovarian cancer (A2780) by employing of MTT assay. The obtained results were compared with standard drug as etoposide. Among the tested derivatives, five derivatives ( 10a, 10d, 10e, 10f and 10j ) were revealed most promising activities Specifically, two compounds 10d (PC3=0.77±0.032 µM; A549=0.078±0.0051 µM; MCF-7 = 0.44±0.061 µM and A2780=1.46±0.92 µM) and 10e (PC3=0.03±0.0063 µM; A549=0.021±0.0075 µM; MCF-7 = 0.19±0.084 µM and A2780=0.11±0.064 µM) possessed highest anticancer activity." @default.
- W3174948003 created "2021-07-05" @default.
- W3174948003 creator A5047765657 @default.
- W3174948003 creator A5081791743 @default.
- W3174948003 creator A5085718694 @default.
- W3174948003 date "2021-08-01" @default.
- W3174948003 modified "2023-09-23" @default.
- W3174948003 title "Design, synthesis and anticancer evaluation of chalcone based thieno[2,3-d]thiazoles as anticancer agents" @default.
- W3174948003 cites W1066801960 @default.
- W3174948003 cites W1588756369 @default.
- W3174948003 cites W1849218084 @default.
- W3174948003 cites W1929853724 @default.
- W3174948003 cites W1970428333 @default.
- W3174948003 cites W1972226982 @default.
- W3174948003 cites W1972231326 @default.
- W3174948003 cites W1978812786 @default.
- W3174948003 cites W2014106971 @default.
- W3174948003 cites W2016843600 @default.
- W3174948003 cites W2022150699 @default.
- W3174948003 cites W2022864983 @default.
- W3174948003 cites W2039799458 @default.
- W3174948003 cites W2053883744 @default.
- W3174948003 cites W2053955788 @default.
- W3174948003 cites W2059204844 @default.
- W3174948003 cites W2062042038 @default.
- W3174948003 cites W2078338300 @default.
- W3174948003 cites W2086685211 @default.
- W3174948003 cites W2126340169 @default.
- W3174948003 cites W2175794497 @default.
- W3174948003 cites W2285824801 @default.
- W3174948003 cites W2345617283 @default.
- W3174948003 cites W2418293022 @default.
- W3174948003 cites W2466291567 @default.
- W3174948003 cites W2468291556 @default.
- W3174948003 cites W2569872293 @default.
- W3174948003 cites W2773556861 @default.
- W3174948003 cites W2792926295 @default.
- W3174948003 cites W2793929067 @default.
- W3174948003 cites W2794660860 @default.
- W3174948003 cites W2947421309 @default.
- W3174948003 cites W2952656992 @default.
- W3174948003 cites W2964605671 @default.
- W3174948003 cites W2997313217 @default.
- W3174948003 cites W3017749475 @default.
- W3174948003 doi "https://doi.org/10.1016/j.cdc.2021.100742" @default.
- W3174948003 hasPublicationYear "2021" @default.
- W3174948003 type Work @default.
- W3174948003 sameAs 3174948003 @default.
- W3174948003 citedByCount "2" @default.
- W3174948003 countsByYear W31749480032022 @default.
- W3174948003 countsByYear W31749480032023 @default.
- W3174948003 crossrefType "journal-article" @default.
- W3174948003 hasAuthorship W3174948003A5047765657 @default.
- W3174948003 hasAuthorship W3174948003A5081791743 @default.
- W3174948003 hasAuthorship W3174948003A5085718694 @default.
- W3174948003 hasConcept C121608353 @default.
- W3174948003 hasConcept C126322002 @default.
- W3174948003 hasConcept C143998085 @default.
- W3174948003 hasConcept C185592680 @default.
- W3174948003 hasConcept C190283241 @default.
- W3174948003 hasConcept C2776256026 @default.
- W3174948003 hasConcept C2776694085 @default.
- W3174948003 hasConcept C2778119113 @default.
- W3174948003 hasConcept C2780035454 @default.
- W3174948003 hasConcept C2780192828 @default.
- W3174948003 hasConcept C2780427987 @default.
- W3174948003 hasConcept C2780764945 @default.
- W3174948003 hasConcept C2780783641 @default.
- W3174948003 hasConcept C3018146709 @default.
- W3174948003 hasConcept C55493867 @default.
- W3174948003 hasConcept C71240020 @default.
- W3174948003 hasConcept C71924100 @default.
- W3174948003 hasConcept C98274493 @default.
- W3174948003 hasConceptScore W3174948003C121608353 @default.
- W3174948003 hasConceptScore W3174948003C126322002 @default.
- W3174948003 hasConceptScore W3174948003C143998085 @default.
- W3174948003 hasConceptScore W3174948003C185592680 @default.
- W3174948003 hasConceptScore W3174948003C190283241 @default.
- W3174948003 hasConceptScore W3174948003C2776256026 @default.
- W3174948003 hasConceptScore W3174948003C2776694085 @default.
- W3174948003 hasConceptScore W3174948003C2778119113 @default.
- W3174948003 hasConceptScore W3174948003C2780035454 @default.
- W3174948003 hasConceptScore W3174948003C2780192828 @default.
- W3174948003 hasConceptScore W3174948003C2780427987 @default.
- W3174948003 hasConceptScore W3174948003C2780764945 @default.
- W3174948003 hasConceptScore W3174948003C2780783641 @default.
- W3174948003 hasConceptScore W3174948003C3018146709 @default.
- W3174948003 hasConceptScore W3174948003C55493867 @default.
- W3174948003 hasConceptScore W3174948003C71240020 @default.
- W3174948003 hasConceptScore W3174948003C71924100 @default.
- W3174948003 hasConceptScore W3174948003C98274493 @default.
- W3174948003 hasLocation W31749480031 @default.
- W3174948003 hasOpenAccess W3174948003 @default.
- W3174948003 hasPrimaryLocation W31749480031 @default.
- W3174948003 hasRelatedWork W1982347917 @default.
- W3174948003 hasRelatedWork W2027388151 @default.
- W3174948003 hasRelatedWork W2090099591 @default.
- W3174948003 hasRelatedWork W2366577297 @default.