Matches in SemOpenAlex for { <https://semopenalex.org/work/W3175003232> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W3175003232 abstract "Abstract Background Erenumab, a monoclonal antibody against the calcitonin gene-related peptide (CGRP) receptor, is registered for migraine prevention. Compared to other conventional migraine prevention medicines (i.e. topiramate, betablockers and amitriptyline) erenumab has better tolerability. Impaired hemostasis has not been reported previously. Here, we report the first case of an increased tendency to bruise in a migraine patient treated with erenumab. Case presentation A 41-year old female migraine patient was treated with erenumab for 12 months, which led to a significant reduction of headache and migraine days. Three months after treatment start, she experienced increased tendency to bruise leading to extreme ecchymosis after 4 months treatment. Platelet counts and aggregation, thromboelastography, activated partial thromboplastin time (APTT) and international normalized ratio (INR) were all normal. Thorough interview revealed intake of fish oil supplements for many years prior to treatment. The increased tendency to bruise subsided after discontinuation of fish oil supplements. Conclusion The combination of fish oil supplements and erenumab may cause increased tendency to bruise. Erenumab has no effect on the platelets per se but may cause impaired wound healing by suppression of CGRP. Thus, small and unnoticeable bruises may be aggravated instead in patients with tendency to bruise caused by for instance fish oil supplements." @default.
- W3175003232 created "2021-07-05" @default.
- W3175003232 creator A5023775224 @default.
- W3175003232 creator A5058013247 @default.
- W3175003232 creator A5062145681 @default.
- W3175003232 creator A5062653314 @default.
- W3175003232 creator A5075370802 @default.
- W3175003232 date "2021-07-02" @default.
- W3175003232 modified "2023-10-10" @default.
- W3175003232 title "Extreme ecchymoses in a migraine patient using concomitant treatment with calcitonin gene-related peptide receptor antibodies and fish oil supplements: a case report" @default.
- W3175003232 cites W1982272966 @default.
- W3175003232 cites W2084961143 @default.
- W3175003232 cites W2162942726 @default.
- W3175003232 cites W2173487576 @default.
- W3175003232 cites W2944253406 @default.
- W3175003232 cites W2948005364 @default.
- W3175003232 cites W3035566232 @default.
- W3175003232 cites W4254908862 @default.
- W3175003232 doi "https://doi.org/10.1186/s12883-021-02294-6" @default.
- W3175003232 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8252281" @default.
- W3175003232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34215196" @default.
- W3175003232 hasPublicationYear "2021" @default.
- W3175003232 type Work @default.
- W3175003232 sameAs 3175003232 @default.
- W3175003232 citedByCount "3" @default.
- W3175003232 countsByYear W31750032322022 @default.
- W3175003232 countsByYear W31750032322023 @default.
- W3175003232 crossrefType "journal-article" @default.
- W3175003232 hasAuthorship W3175003232A5023775224 @default.
- W3175003232 hasAuthorship W3175003232A5058013247 @default.
- W3175003232 hasAuthorship W3175003232A5062145681 @default.
- W3175003232 hasAuthorship W3175003232A5062653314 @default.
- W3175003232 hasAuthorship W3175003232A5075370802 @default.
- W3175003232 hasBestOaLocation W31750032321 @default.
- W3175003232 hasConcept C126322002 @default.
- W3175003232 hasConcept C141071460 @default.
- W3175003232 hasConcept C197934379 @default.
- W3175003232 hasConcept C2778375690 @default.
- W3175003232 hasConcept C2778541695 @default.
- W3175003232 hasConcept C2778715236 @default.
- W3175003232 hasConcept C2779663748 @default.
- W3175003232 hasConcept C2781424195 @default.
- W3175003232 hasConcept C71924100 @default.
- W3175003232 hasConceptScore W3175003232C126322002 @default.
- W3175003232 hasConceptScore W3175003232C141071460 @default.
- W3175003232 hasConceptScore W3175003232C197934379 @default.
- W3175003232 hasConceptScore W3175003232C2778375690 @default.
- W3175003232 hasConceptScore W3175003232C2778541695 @default.
- W3175003232 hasConceptScore W3175003232C2778715236 @default.
- W3175003232 hasConceptScore W3175003232C2779663748 @default.
- W3175003232 hasConceptScore W3175003232C2781424195 @default.
- W3175003232 hasConceptScore W3175003232C71924100 @default.
- W3175003232 hasIssue "1" @default.
- W3175003232 hasLocation W31750032321 @default.
- W3175003232 hasLocation W31750032322 @default.
- W3175003232 hasOpenAccess W3175003232 @default.
- W3175003232 hasPrimaryLocation W31750032321 @default.
- W3175003232 hasRelatedWork W2060423418 @default.
- W3175003232 hasRelatedWork W2137547383 @default.
- W3175003232 hasRelatedWork W2614836996 @default.
- W3175003232 hasRelatedWork W2792428998 @default.
- W3175003232 hasRelatedWork W2807256989 @default.
- W3175003232 hasRelatedWork W2854566632 @default.
- W3175003232 hasRelatedWork W2937977035 @default.
- W3175003232 hasRelatedWork W3206572053 @default.
- W3175003232 hasRelatedWork W4200628345 @default.
- W3175003232 hasRelatedWork W4250927101 @default.
- W3175003232 hasVolume "21" @default.
- W3175003232 isParatext "false" @default.
- W3175003232 isRetracted "false" @default.
- W3175003232 magId "3175003232" @default.
- W3175003232 workType "article" @default.