Matches in SemOpenAlex for { <https://semopenalex.org/work/W3175139459> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W3175139459 abstract "There is a relationship between sucrose feeding and arterial hypertension. The objective of this study was to investigate, in rats with overload of sucrose in diet, the effect on cardiac output (CO) and total peripheral resistance (TPR). The effects of sucrose on sympathetic nervous system (SS) and renin-angiotensin system (RAS) were also evaluated. Wistar rats (150–220g) were treated for 30 days with sucrose solution (20%) instead of drink water (SC; n=10), the control group (C; n=9) had tap water ad libitum. Mean arterial pressure (MAP), CO and TPR were “on line” recorded in a Cardiomax system. The effects of sympathetic and angiotensinergic system blockade on hemodynamics parameters were evaluated by hexamethonium and captopril administration, respectively. Circulating levels of angiotensin I and II were determined by HPLC. An increase in MAP was observed in SC (128±1mmHg) compared with C (102±4 mmHg) meditated by a TPR increase (SC 1,39±0,03 and, C 0,93±0,11 mmHg/mL/min). The sympathetic blockade caused a larger fall in MAP in C (from 102±4 to 51±0,5 mmHg) than in SC (from 128±1 to 75±1 mmHg). However, the depressor response to captopril was larger in SC (from 97±2 to 58±2 mmHg) than in C (from 80±2 to 68±2 mmHg). There was a reduction in circulating AngioI levels in SC (80±10 ng/mL) in relation to C (193±27 ng/mL). However, AngioII was higher in SC (421±41 ng/mL) compared with C (302±10 ng/mL). Taken altogether, the results show that an overload of sucrose in the diet caused increase in MAP due to TPR. The hypertension was related to an increase in circulating AngioII. Supported by FAPESP; CNPq (PRONEX)." @default.
- W3175139459 created "2021-07-05" @default.
- W3175139459 creator A5002962628 @default.
- W3175139459 creator A5005421347 @default.
- W3175139459 creator A5020457262 @default.
- W3175139459 creator A5050322140 @default.
- W3175139459 creator A5063161853 @default.
- W3175139459 creator A5077312680 @default.
- W3175139459 date "2006-03-01" @default.
- W3175139459 modified "2023-10-01" @default.
- W3175139459 title "CHRONIC EFFECTS OF SUCROSE INGESTION ON METABOLIC AND HEMODYNAMIC PARAMETERS IN RATS" @default.
- W3175139459 doi "https://doi.org/10.1096/fasebj.20.4.a735-d" @default.
- W3175139459 hasPublicationYear "2006" @default.
- W3175139459 type Work @default.
- W3175139459 sameAs 3175139459 @default.
- W3175139459 citedByCount "0" @default.
- W3175139459 crossrefType "journal-article" @default.
- W3175139459 hasAuthorship W3175139459A5002962628 @default.
- W3175139459 hasAuthorship W3175139459A5005421347 @default.
- W3175139459 hasAuthorship W3175139459A5020457262 @default.
- W3175139459 hasAuthorship W3175139459A5050322140 @default.
- W3175139459 hasAuthorship W3175139459A5063161853 @default.
- W3175139459 hasAuthorship W3175139459A5077312680 @default.
- W3175139459 hasConcept C126322002 @default.
- W3175139459 hasConcept C164705383 @default.
- W3175139459 hasConcept C178853913 @default.
- W3175139459 hasConcept C185592680 @default.
- W3175139459 hasConcept C193230392 @default.
- W3175139459 hasConcept C2778597767 @default.
- W3175139459 hasConcept C31903555 @default.
- W3175139459 hasConcept C71924100 @default.
- W3175139459 hasConceptScore W3175139459C126322002 @default.
- W3175139459 hasConceptScore W3175139459C164705383 @default.
- W3175139459 hasConceptScore W3175139459C178853913 @default.
- W3175139459 hasConceptScore W3175139459C185592680 @default.
- W3175139459 hasConceptScore W3175139459C193230392 @default.
- W3175139459 hasConceptScore W3175139459C2778597767 @default.
- W3175139459 hasConceptScore W3175139459C31903555 @default.
- W3175139459 hasConceptScore W3175139459C71924100 @default.
- W3175139459 hasFunder F4320320997 @default.
- W3175139459 hasFunder F4320322025 @default.
- W3175139459 hasIssue "4" @default.
- W3175139459 hasLocation W31751394591 @default.
- W3175139459 hasOpenAccess W3175139459 @default.
- W3175139459 hasPrimaryLocation W31751394591 @default.
- W3175139459 hasRelatedWork W1531601525 @default.
- W3175139459 hasRelatedWork W2021696517 @default.
- W3175139459 hasRelatedWork W2049397185 @default.
- W3175139459 hasRelatedWork W2159512267 @default.
- W3175139459 hasRelatedWork W2304633692 @default.
- W3175139459 hasRelatedWork W2399063111 @default.
- W3175139459 hasRelatedWork W2748952813 @default.
- W3175139459 hasRelatedWork W2899084033 @default.
- W3175139459 hasRelatedWork W2948807893 @default.
- W3175139459 hasRelatedWork W2778153218 @default.
- W3175139459 hasVolume "20" @default.
- W3175139459 isParatext "false" @default.
- W3175139459 isRetracted "false" @default.
- W3175139459 magId "3175139459" @default.
- W3175139459 workType "article" @default.