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• W3175376837 endingPage "275" @default.
• W3175376837 startingPage "259" @default.
• W3175376837 abstract "The approach to surgical patients with renal failure is rapidly evolving. Indeed, the concept of renal failure itself has been refined over the last two decades. Acute renal failure, now referred to as acute kidney injury (AKI), has become increasingly recognized as a signal of perioperative harm. Chronic renal failure is now recognized as a progressive spectrum of disease ranging from mild impairment in glomerular filtration to end-stage renal disease (ESRD) requiring renal replacement therapy or transplantation. Each stage of chronic kidney disease (CKD) confers increasing perioperative cardiovascular risk. Importantly, worse CKD also appears to increase the risk of AKI. AKI itself may accelerate the progression of CKD. Preventing AKI in the perioperative period potentially reduces long-term comorbidity among patients with CKD. Age is highly associated with CKD. As the surgical population ages, the number of patients with CKD is expected to increase. A special approach is required for patients with ESRD because ESRD is associated with high cardiovascular morbidity, the need for perioperative dialysis, and altered pharmacology. When patients with ESRD receive a kidney transplant, many of the perioperative principles apply but with the added focus on ensuring graft viability. Recent changes in the United States kidney allocation system will most likely expand access to less viable kidneys to sicker patients, which is likely to pose unique challenges to the perioperative physician." @default.
• W3175376837 created "2021-07-05" @default.
• W3175376837 creator A5073324071 @default.
• W3175376837 creator A5088822634 @default.
• W3175376837 date "2022-01-01" @default.
• W3175376837 modified "2023-09-25" @default.
• W3175376837 title "Perioperative Management of Renal Failure and Renal Transplant" @default.
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