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- W3175462614 endingPage "773" @default.
- W3175462614 startingPage "773" @default.
- W3175462614 abstract "After stroke, dynamic changes take place from necrotic-apoptotic continuum, inflammatory response to poststroke neurogenesis, and remodeling of the network. These changes and baseline brain pathology such as small vessel disease (SVD) and amyloid burden may be associated with the occurrence of early or late poststroke cognitive impairment (PSCI) or dementia (PSD), which affect not only stroke victims but also their families and even society. We reviewed the current concepts and understanding of the pathophysiology for PSCI/PSD and identified useful tools for the diagnosis and the prediction of PSCI in serological, CSF, and image characteristics. Then, we untangled their relationships with blood pressure (BP) and blood pressure variability (BPV), important but often overlooked risk factors for PSCI/PSD. Finally, we provided evidence for the modifying effects of BP and BPV on PSCI as well as pharmacological and non-pharmacological interventions and life style modification for PSCI/PSD prevention and treatment." @default.
- W3175462614 created "2021-07-05" @default.
- W3175462614 creator A5012483729 @default.
- W3175462614 creator A5063414739 @default.
- W3175462614 creator A5087199890 @default.
- W3175462614 date "2021-07-02" @default.
- W3175462614 modified "2023-10-01" @default.
- W3175462614 title "Association between Blood Pressure, Blood Pressure Variability, and Post-Stroke Cognitive Impairment" @default.
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