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- W317548049 abstract "which interfere with redox processes. Drug effiux via a multidrug resistance membrane protein, and the production of a protein competing with the drug for the target heroin are thought to be responsible for resistance to blood schizontocides. Structural changes in target enzymes are responsible for easily-developed resistance to antifolatcs and antimitochondrials. The judicious use of drug combinations can help to avoid development of resistance and combat resistant infections, but new drugs are urgently needed." @default.
- W317548049 created "2016-06-24" @default.
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- W317548049 date "1999-01-01" @default.
- W317548049 modified "2023-09-27" @default.
- W317548049 title "Drug Resistance in Plasmodium falciparum Malaria Summary: Four classes of drugs are reviewed: blood schizontocides acting only on the hemoglobin-digesting blood stages, the antifolates which attack tetrahydrofolate synthesis in all the growing stages, antimitochondrials affecting synthesis and electron transport, and 8-aminoquinolines" @default.
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