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- W3176003330 abstract "Olive oil is an important food with interesting functional properties and is widely indicated as a hypolipidemic, oxidative stress reliever and hypolipidemic agent due to its chemical structures and biological functions. The present study analyzed the hypoglycaemic, hypolipidemic, technological, and sensory potential of 4-methoxycinnamic acid (PCO–C) diester aggregate olive oil, obtained from the wax powder from carnauba (Copernicia prunifera). Zebrafish was used as an experimental obesity model. After developing obesity, with hyperglycemia and hyperlipidemia, fishes were submitted to extra virgin olive oil aggregated to 4-methoxycinnamic acid diester (PCO–C + AZ) or not, for 4 days. Also, the product PCO–C + AZ was submitted to rheological and sensory analysis. The PCO–C + AZ shown a 43% reduction (p < 0.01) in blood glucose and the rheological findings did not show any change in the quality parameters of olive oil due to the aggregation to PCO–C. Oil + PCO–C (100 mg/kg) was able to reduce (***p < 0.001) cholesterol and triacylglycerol levels of animals in the treatment group when compared to animals in the control group. In addition, all the treatments used were able to significantly reduce the hepatic levels of reactive oxygen species ((**p < 0.01 vs. Control). Additionally, the acceptability of the product shown all acceptability index (IA%) parameters above 70%. Thus, we concluded that the product PCO–C + AZ has a hypoglycaemic effect, presenting quality parameters very similar to the original extra virgin olive oil." @default.
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- W3176003330 date "2021-12-01" @default.
- W3176003330 modified "2023-10-01" @default.
- W3176003330 title "Therapeutical effect of olive oil aggregate to 4-methoxycinnamic acid diester obtained from carnauba (Copernicia prunifera) wax (PCO–C) on dyslipidemia, hyperglycemia, and oxidative stress" @default.
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- W3176003330 doi "https://doi.org/10.1016/j.fbio.2021.101216" @default.
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