Matches in SemOpenAlex for { <https://semopenalex.org/work/W3176088377> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3176088377 endingPage "222" @default.
- W3176088377 startingPage "217" @default.
- W3176088377 abstract "Aim:Digoxin is an anti-arrhythmic drug that also has a positive inotropic property. It is mainly used to control heart rate in nonvalvular atrial fibrillation, and improve ejection fraction in heart failure. In recent years, the frequency of digoxin and a combination of new drug using has been increasing. Therefore, to assess the pharmacokinetic interaction between direct oral anticoagulant agents and cardiovascular drugs is necessary for intoxications. Material and Methods:Patients Serum Digoxin Concentrations levels and digoxin intoxications were evaluated according to risk factors investigated retrospectively Patients Serum Digoxin Concentrations levels <1 ng/ml is accepted as low, 1-2 ng/ml therapeutic range, 2.1-2.4 ng/ml is high and >2.4 ng/ml toxicity. Results:The study consisted of 248 females (60.2%) and 160 males (39.2%). The mean age of the patients was 70.5 years. The average age of patients was 70.5 years. Serum digoxin concentrations of 408 patients; 44.81% were detected in the low therapeutic range, 34.41% in the therapeutic range, 6.23% in the high therapeutic range, 14.55% in the toxic therapeutic range. The mean glomerular filtration rate was 58.45, and the mean Serum Digoxin Concentration was 1.36 ng/ml. The statistically significant relationship between age and Patients Serum Digoxin Concentration was 16.3% (p <0.05). There was a statistically significant relationship between Glomerular Filtration Rate and Serum Digoxin Concentrations; one increased and the other decreased (p <0.05). In patients without atherosclerotic heart disease, Serum Digoxin Concentration was significantly lower than those with atherosclerotic heart disease(p< 0.05). Serum Digoxin Concentrations were significantly higher in patients treated with rivaroxaban, the proportions of which differ significantly from each other at the 0.05 level. Conclusion:Nowadays, the frequency of using digoxin and direct oral anticoagulants together is increasing. The narrow therapeutic level of digoxin necessitates close monitoring due to drug-drug interactions." @default.
- W3176088377 created "2021-07-05" @default.
- W3176088377 creator A5007343292 @default.
- W3176088377 creator A5017200785 @default.
- W3176088377 creator A5024053931 @default.
- W3176088377 creator A5052891647 @default.
- W3176088377 creator A5073001339 @default.
- W3176088377 date "2021-06-30" @default.
- W3176088377 modified "2023-09-23" @default.
- W3176088377 title "Evaluating high serum digoxin concentration risk factors interaction between direct oral anticoagulant agents and digoxin" @default.
- W3176088377 cites W1591811204 @default.
- W3176088377 cites W180260989 @default.
- W3176088377 cites W2002132710 @default.
- W3176088377 cites W2005753373 @default.
- W3176088377 cites W2016380061 @default.
- W3176088377 cites W2020449031 @default.
- W3176088377 cites W2093626671 @default.
- W3176088377 cites W2106203125 @default.
- W3176088377 cites W2113561246 @default.
- W3176088377 cites W2150184024 @default.
- W3176088377 cites W2152623033 @default.
- W3176088377 cites W2158987804 @default.
- W3176088377 cites W2172196157 @default.
- W3176088377 cites W2214982419 @default.
- W3176088377 cites W2516329549 @default.
- W3176088377 cites W2549557285 @default.
- W3176088377 cites W2788179248 @default.
- W3176088377 cites W2892838586 @default.
- W3176088377 cites W2916505054 @default.
- W3176088377 cites W2945068164 @default.
- W3176088377 cites W3023363600 @default.
- W3176088377 cites W3114504396 @default.
- W3176088377 cites W4206159607 @default.
- W3176088377 cites W4237617682 @default.
- W3176088377 doi "https://doi.org/10.18663/tjcl.952903" @default.
- W3176088377 hasPublicationYear "2021" @default.
- W3176088377 type Work @default.
- W3176088377 sameAs 3176088377 @default.
- W3176088377 citedByCount "0" @default.
- W3176088377 crossrefType "journal-article" @default.
- W3176088377 hasAuthorship W3176088377A5007343292 @default.
- W3176088377 hasAuthorship W3176088377A5017200785 @default.
- W3176088377 hasAuthorship W3176088377A5024053931 @default.
- W3176088377 hasAuthorship W3176088377A5052891647 @default.
- W3176088377 hasAuthorship W3176088377A5073001339 @default.
- W3176088377 hasBestOaLocation W31760883771 @default.
- W3176088377 hasConcept C112705442 @default.
- W3176088377 hasConcept C126322002 @default.
- W3176088377 hasConcept C134018914 @default.
- W3176088377 hasConcept C159641895 @default.
- W3176088377 hasConcept C19831878 @default.
- W3176088377 hasConcept C2777707475 @default.
- W3176088377 hasConcept C2778198053 @default.
- W3176088377 hasConcept C2779161974 @default.
- W3176088377 hasConcept C2780035454 @default.
- W3176088377 hasConcept C2780272996 @default.
- W3176088377 hasConcept C3020081911 @default.
- W3176088377 hasConcept C71924100 @default.
- W3176088377 hasConcept C78085059 @default.
- W3176088377 hasConcept C90924648 @default.
- W3176088377 hasConcept C98274493 @default.
- W3176088377 hasConceptScore W3176088377C112705442 @default.
- W3176088377 hasConceptScore W3176088377C126322002 @default.
- W3176088377 hasConceptScore W3176088377C134018914 @default.
- W3176088377 hasConceptScore W3176088377C159641895 @default.
- W3176088377 hasConceptScore W3176088377C19831878 @default.
- W3176088377 hasConceptScore W3176088377C2777707475 @default.
- W3176088377 hasConceptScore W3176088377C2778198053 @default.
- W3176088377 hasConceptScore W3176088377C2779161974 @default.
- W3176088377 hasConceptScore W3176088377C2780035454 @default.
- W3176088377 hasConceptScore W3176088377C2780272996 @default.
- W3176088377 hasConceptScore W3176088377C3020081911 @default.
- W3176088377 hasConceptScore W3176088377C71924100 @default.
- W3176088377 hasConceptScore W3176088377C78085059 @default.
- W3176088377 hasConceptScore W3176088377C90924648 @default.
- W3176088377 hasConceptScore W3176088377C98274493 @default.
- W3176088377 hasIssue "2" @default.
- W3176088377 hasLocation W31760883771 @default.
- W3176088377 hasLocation W31760883772 @default.
- W3176088377 hasOpenAccess W3176088377 @default.
- W3176088377 hasPrimaryLocation W31760883771 @default.
- W3176088377 hasRelatedWork W1559629775 @default.
- W3176088377 hasRelatedWork W1985799882 @default.
- W3176088377 hasRelatedWork W1987811077 @default.
- W3176088377 hasRelatedWork W2039536404 @default.
- W3176088377 hasRelatedWork W2356390486 @default.
- W3176088377 hasRelatedWork W2387250905 @default.
- W3176088377 hasRelatedWork W2417287318 @default.
- W3176088377 hasRelatedWork W2419039661 @default.
- W3176088377 hasRelatedWork W2420918848 @default.
- W3176088377 hasRelatedWork W2437116649 @default.
- W3176088377 hasVolume "12" @default.
- W3176088377 isParatext "false" @default.
- W3176088377 isRetracted "false" @default.
- W3176088377 magId "3176088377" @default.
- W3176088377 workType "article" @default.