FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3176146153> ?p ?o ?g. }

• W3176146153 endingPage "1696" @default.
• W3176146153 startingPage "1685" @default.
• W3176146153 abstract "Abstract Intensive and overuse of antibiotics during the last years has triggered a distinct rise in antibiotic resistance worldwide. In addition to the newly developed antimicrobials, there is a high demand for alternative treatment options against persistent bacterial infections. The biocidal impact of metal ions like copper (Cu 2+ ), silver (Ag + ), and zinc (Zn 2+ ), also known as the oligodynamic effect has been used for ages to kill or inhibit the growth of microorganisms and to employ long‐term prevention strategies against their biological antagonists. Herein, we report on the synthesis of Cu, Ag, and Zn metal and corresponding oxide nanoparticles immobilized on hollow mesoporous silica capsules (HMSCs) obtained by a hard‐template assisted sol‐gel synthesis followed by reduction of appropriate metal salts in the presence of HMSCs. Compartmentalization of nanosized metal and oxide clusters in Ag@HMSCs, Cu@HMSCs, and ZnO@HMSCs particles prevented their agglomeration and offered high release kinetics of metal ions between 2.0 and 3.7 mM during 24 h, as monitored by UV‐vis analyses. The distribution and morphology of pristine and metal functionalized HMSCs were evaluated by transmission electron microscopy analysis revealing the successful synthesis of Ag, Cu, and ZnO nanoparticles supported on HMSCs. X‐ray photoelectron spectroscopy revealed that mainly Cu(II), Ag(0), and Zn(II) species were present in the modified HMSCs. In addition to the surface attachment of preformed metal (Ag and Cu) and metal oxide (ZnO) cluster, nucleation of metal nanoparticles inside the void of HMSCs provided an internal reservoir which allowed for a time‐dependent release of metal ions through slower dissolution rates leading to a long‐term and sustained bacterial inhibition over several hours. The high antimicrobial efficiency of Ag@HMSCs, Cu@HMSCs, and ZnO@HMSCs particles was investigated toward both Gram‐positive ( Bacillus subtilis ) and Gram‐negative ( Escherichia coli ) bacteria by INT assays showing a complete growth inhibition for both bacteria types after 24 h. While Ag@HMSCs and Cu@HMSCs showed a higher susceptibility against Gram‐negative bacteria, ZnO@HMSCs showed a higher susceptibility against Gram‐positive bacteria. This demonstrates the promise of metal‐loaded capsules as antibacterial delivery vehicles with dual‐mode time‐release profiles being potential alternatives for antibiotic drugs." @default.
• W3176146153 created "2021-07-05" @default.
• W3176146153 creator A5001656610 @default.
• W3176146153 creator A5002349377 @default.
• W3176146153 creator A5005863881 @default.
• W3176146153 creator A5029912532 @default.
• W3176146153 creator A5033208692 @default.
• W3176146153 creator A5043653660 @default.
• W3176146153 creator A5053148731 @default.
• W3176146153 creator A5058910198 @default.
• W3176146153 creator A5064991508 @default.
• W3176146153 date "2021-07-21" @default.
• W3176146153 modified "2023-10-18" @default.
• W3176146153 title "Hollow mesoporous silica capsules loaded with copper, silver, and zinc oxide nanoclusters for sustained antibacterial efficacy" @default.
• W3176146153 cites W1582426659 @default.
• W3176146153 cites W1977825829 @default.
• W3176146153 cites W1979020653 @default.
• W3176146153 cites W1984640091 @default.
• W3176146153 cites W1990006102 @default.
• W3176146153 cites W1990681348 @default.
• W3176146153 cites W1991958151 @default.
• W3176146153 cites W1993950777 @default.
• W3176146153 cites W1996796384 @default.
• W3176146153 cites W1999866520 @default.
• W3176146153 cites W2005314165 @default.
• W3176146153 cites W2015409516 @default.
• W3176146153 cites W2018517592 @default.
• W3176146153 cites W2019908525 @default.
• W3176146153 cites W2023348863 @default.
• W3176146153 cites W2031002662 @default.
• W3176146153 cites W2043000592 @default.
• W3176146153 cites W2055144185 @default.
• W3176146153 cites W2066252060 @default.
• W3176146153 cites W2067869089 @default.
• W3176146153 cites W2070780121 @default.
• W3176146153 cites W2072567873 @default.
• W3176146153 cites W2078735798 @default.
• W3176146153 cites W2103629556 @default.
• W3176146153 cites W2146482929 @default.
• W3176146153 cites W2147819711 @default.
• W3176146153 cites W2148260760 @default.
• W3176146153 cites W2149023620 @default.
• W3176146153 cites W2220528754 @default.
• W3176146153 cites W2317692628 @default.
• W3176146153 cites W2334989887 @default.
• W3176146153 cites W2512609984 @default.
• W3176146153 cites W2571178857 @default.
• W3176146153 cites W2589067428 @default.
• W3176146153 cites W2621055749 @default.
• W3176146153 cites W2747001756 @default.
• W3176146153 cites W2772995273 @default.
• W3176146153 cites W2792428520 @default.
• W3176146153 cites W2796156410 @default.
• W3176146153 cites W2848635099 @default.
• W3176146153 cites W2898135039 @default.
• W3176146153 cites W2939564313 @default.
• W3176146153 cites W2973182801 @default.
• W3176146153 cites W3088059468 @default.
• W3176146153 cites W3092582261 @default.
• W3176146153 cites W4235574122 @default.
• W3176146153 doi "https://doi.org/10.1111/jace.18002" @default.
• W3176146153 hasPublicationYear "2021" @default.
• W3176146153 type Work @default.
• W3176146153 sameAs 3176146153 @default.
• W3176146153 citedByCount "3" @default.
• W3176146153 countsByYear W31761461532022 @default.
• W3176146153 countsByYear W31761461532023 @default.
• W3176146153 crossrefType "journal-article" @default.
• W3176146153 hasAuthorship W3176146153A5001656610 @default.
• W3176146153 hasAuthorship W3176146153A5002349377 @default.
• W3176146153 hasAuthorship W3176146153A5005863881 @default.
• W3176146153 hasAuthorship W3176146153A5029912532 @default.
• W3176146153 hasAuthorship W3176146153A5033208692 @default.
• W3176146153 hasAuthorship W3176146153A5043653660 @default.
• W3176146153 hasAuthorship W3176146153A5053148731 @default.
• W3176146153 hasAuthorship W3176146153A5058910198 @default.
• W3176146153 hasAuthorship W3176146153A5064991508 @default.
• W3176146153 hasBestOaLocation W31761461531 @default.
• W3176146153 hasConcept C127413603 @default.
• W3176146153 hasConcept C138631740 @default.
• W3176146153 hasConcept C13965031 @default.
• W3176146153 hasConcept C155672457 @default.
• W3176146153 hasConcept C161790260 @default.
• W3176146153 hasConcept C171250308 @default.
• W3176146153 hasConcept C175708663 @default.
• W3176146153 hasConcept C178790620 @default.
• W3176146153 hasConcept C185592680 @default.
• W3176146153 hasConcept C191897082 @default.
• W3176146153 hasConcept C192562407 @default.
• W3176146153 hasConcept C2778402822 @default.
• W3176146153 hasConcept C2779851234 @default.
• W3176146153 hasConcept C42360764 @default.
• W3176146153 hasConcept C535196362 @default.
• W3176146153 hasConcept C544153396 @default.
• W3176146153 hasConcept C544778455 @default.
• W3176146153 hasConcept C61048295 @default.
• W3176146153 hasConcept C82776694 @default.
• W3176146153 hasConceptScore W3176146153C127413603 @default.

• next