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- W3176164480 abstract "Liquid wastes (LW) disposed in hospital handwashing sinks may affect colonization of sink P-traps by carbapenemase-producing Klebsiella pneumoniae (CPKP), causing CPKP dispersal into the patient care environment. This study aimed to determine the effect of LW on biofilm formation and CPKP colonization in a P-Trap model (PTM). PTMs containing polymicrobial biofilms grown in autoclaved municipal tap water (ATW) supplemented with 5% dextrose in water (D5W), nutritional shake (Shake), sugar-based soft drink (Soda), or ATW were inoculated with K. pneumoniae ST258 KPC+ (ST258) or K. pneumoniae CAV1016 (CAV1016) and sampled after 7, 14, and 21 d. Biofilm bio-volume, mean thickness, and heterotrophic plate counts were significantly reduced and roughness coefficient significantly increased by Soda compared with D5W, Shake, or ATW. CPKP were significantly reduced by Soda but significantly amplified by D5W (ST258; CAV1016, 7 d) and Shake (ST258) suggesting that reducing LW disposal in sinks may reduce CPKP dispersal into patient care environments." @default.
- W3176164480 created "2021-07-05" @default.
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- W3176164480 date "2021-05-28" @default.
- W3176164480 modified "2023-09-27" @default.
- W3176164480 title "Supplemental nutrients stimulate the amplification of carbapenemase-producing <i>Klebsiella pneumoniae</i> (CPKP) in a sink drain <i>in vitro</i> biofilm reactor model" @default.
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- W3176164480 doi "https://doi.org/10.1080/08927014.2021.1915998" @default.
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