FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3176334497> ?p ?o ?g. }

• W3176334497 abstract "Stress and rest T1-mapping may assess for myocardial ischemia and extracellular volume (ECV). However, the stress T1 response is method-dependent, and underestimation may lead to misdiagnosis. Further, ECV quantification may be affected by time, as well as the number and dosage of gadolinium (Gd) contrast administered. We compared two commonly available T1-mapping approaches in their stress T1 response and ECV measurement stability. Healthy subjects (n = 10, 50% female, 35 ± 8 years) underwent regadenoson stress CMR (1.5 T) on two separate days. Prototype ShMOLLI 5(1)1(1)1 sequence was used to acquire consecutive mid-ventricular T1-maps at rest, stress and post-Gd contrast to track the T1 time evolution. For comparison, standard MOLLI sequences were used: MOLLI 5(3)3 Low (256 matrix) & High (192 matrix) Heart Rate (HR) to acquire rest and stress T1-maps, and MOLLI 4(1)3(1)2 Low & High HR for post-contrast T1-maps. Stress and rest myocardial blood flow (MBF) maps were acquired after IV Gd contrast (0.05 mmol/kg each). Stress T1 reactivity (delta T1) was defined as the relative percentage increase in native T1 between rest and stress. Myocardial T1 values for delta T1 (dT1) and ECV were calculated. Residuals from the identified time dependencies were used to assess intra-method variability. ShMOLLI achieved a greater stress T1 response compared to MOLLI Low and High HR (peak dT1 = 6.4 ± 1.7% vs. 4.8 ± 1.3% vs. 3.8 ± 1.0%, respectively; both p < 0.0001). ShMOLLI dT1 correlated strongly with stress MBF (r = 0.77, p < 0.001), compared to MOLLI Low HR (r = 0.65, p < 0.01) and MOLLI High HR (r = 0.43, p = 0.07). ShMOLLI ECV was more stable to gadolinium dose with less time drift (0.006-0.04% per minute) than MOLLI variants. Overall, ShMOLLI demonstrated less intra-individual variability than MOLLI variants for stress T1 and ECV quantification. Power calculations indicate up to a fourfold (stress T1) and 7.5-fold (ECV) advantage in sample-size reduction using ShMOLLI. Our results indicate that ShMOLLI correlates strongly with increased MBF during regadenoson stress and achieves a significantly higher stress T1 response, greater effect size, and greater ECV measurement stability compared with the MOLLI variants tested." @default.
• W3176334497 created "2021-07-05" @default.
• W3176334497 creator A5008198032 @default.
• W3176334497 creator A5026760717 @default.
• W3176334497 creator A5028238617 @default.
• W3176334497 creator A5035444537 @default.
• W3176334497 creator A5039837606 @default.
• W3176334497 creator A5069398400 @default.
• W3176334497 creator A5071532306 @default.
• W3176334497 creator A5074710678 @default.
• W3176334497 creator A5078328047 @default.
• W3176334497 creator A5085851683 @default.
• W3176334497 date "2021-06-30" @default.
• W3176334497 modified "2023-10-12" @default.
• W3176334497 title "Cardiac stress T1-mapping response and extracellular volume stability of MOLLI-based T1-mapping methods" @default.
• W3176334497 cites W1555920082 @default.
• W3176334497 cites W1573024517 @default.
• W3176334497 cites W1935234968 @default.
• W3176334497 cites W2023661512 @default.
• W3176334497 cites W2097925909 @default.
• W3176334497 cites W2100721644 @default.
• W3176334497 cites W2102775774 @default.
• W3176334497 cites W2111137674 @default.
• W3176334497 cites W2117828918 @default.
• W3176334497 cites W2117892932 @default.
• W3176334497 cites W2129655528 @default.
• W3176334497 cites W2136177732 @default.
• W3176334497 cites W2137166082 @default.
• W3176334497 cites W2143064593 @default.
• W3176334497 cites W2159285706 @default.
• W3176334497 cites W2193797081 @default.
• W3176334497 cites W2395479392 @default.
• W3176334497 cites W2481017373 @default.
• W3176334497 cites W2529324651 @default.
• W3176334497 cites W2544963635 @default.
• W3176334497 cites W2552563762 @default.
• W3176334497 cites W2605037578 @default.
• W3176334497 cites W2616977749 @default.
• W3176334497 cites W2755248643 @default.
• W3176334497 cites W2763651817 @default.
• W3176334497 cites W2765527908 @default.
• W3176334497 cites W2901419502 @default.
• W3176334497 cites W2903759577 @default.
• W3176334497 cites W2914688717 @default.
• W3176334497 cites W2914756309 @default.
• W3176334497 cites W2946592091 @default.
• W3176334497 cites W2946802813 @default.
• W3176334497 cites W2949082042 @default.
• W3176334497 cites W2957321056 @default.
• W3176334497 cites W2966678998 @default.
• W3176334497 cites W2970323694 @default.
• W3176334497 cites W2974449420 @default.
• W3176334497 cites W2990910366 @default.
• W3176334497 cites W2992568475 @default.
• W3176334497 cites W3012802901 @default.
• W3176334497 cites W3030195953 @default.
• W3176334497 cites W3037970203 @default.
• W3176334497 cites W3083067996 @default.
• W3176334497 cites W3084216491 @default.
• W3176334497 cites W3134176165 @default.
• W3176334497 cites W3135548451 @default.
• W3176334497 cites W3138480930 @default.
• W3176334497 cites W410817826 @default.
• W3176334497 cites W66240855 @default.
• W3176334497 doi "https://doi.org/10.1038/s41598-021-92923-4" @default.
• W3176334497 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8245629" @default.
• W3176334497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34193894" @default.
• W3176334497 hasPublicationYear "2021" @default.
• W3176334497 type Work @default.
• W3176334497 sameAs 3176334497 @default.
• W3176334497 citedByCount "8" @default.
• W3176334497 countsByYear W31763344972021 @default.
• W3176334497 countsByYear W31763344972022 @default.
• W3176334497 countsByYear W31763344972023 @default.
• W3176334497 crossrefType "journal-article" @default.
• W3176334497 hasAuthorship W3176334497A5008198032 @default.
• W3176334497 hasAuthorship W3176334497A5026760717 @default.
• W3176334497 hasAuthorship W3176334497A5028238617 @default.
• W3176334497 hasAuthorship W3176334497A5035444537 @default.
• W3176334497 hasAuthorship W3176334497A5039837606 @default.
• W3176334497 hasAuthorship W3176334497A5069398400 @default.
• W3176334497 hasAuthorship W3176334497A5071532306 @default.
• W3176334497 hasAuthorship W3176334497A5074710678 @default.
• W3176334497 hasAuthorship W3176334497A5078328047 @default.
• W3176334497 hasAuthorship W3176334497A5085851683 @default.
• W3176334497 hasBestOaLocation W31763344971 @default.
• W3176334497 hasConcept C126322002 @default.
• W3176334497 hasConcept C138885662 @default.
• W3176334497 hasConcept C164705383 @default.
• W3176334497 hasConcept C21036866 @default.
• W3176334497 hasConcept C2989005 @default.
• W3176334497 hasConcept C41895202 @default.
• W3176334497 hasConcept C71924100 @default.
• W3176334497 hasConceptScore W3176334497C126322002 @default.
• W3176334497 hasConceptScore W3176334497C138885662 @default.
• W3176334497 hasConceptScore W3176334497C164705383 @default.
• W3176334497 hasConceptScore W3176334497C21036866 @default.
• W3176334497 hasConceptScore W3176334497C2989005 @default.
• W3176334497 hasConceptScore W3176334497C41895202 @default.
• W3176334497 hasConceptScore W3176334497C71924100 @default.

• next