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• W3176350855 endingPage "1353" @default.
• W3176350855 startingPage "1341" @default.
• W3176350855 abstract "Myocardial injury, diagnosed by troponin elevation, is common in COVID-19 patients, but cardiac involvement with clinical manifestations occurs less frequently. We analyzed the literature on COVID-19 (2020) and systematically reviewed the cases where individual patient data were presented. We searched PubMed and Google Scholar for COVID, COVID-19, and coronavirus in combination with myocarditis, heart failure, takotsubo, cardiomyopathy, and cardiogenic shock. We identified 90 cases of COVID-19 with myocardial involvement, mean age 52.9 ± 18.3 years, 54.5% males. Of them, 55 survived (61.1%), 20 died (22.2%), and in 15 (16.7%) the outcome was unknown at the time of publication. Among patients with known outcome, mortality was 26%. The nadir LVEF was 31.7 ± 13.1% and recovered to 50.1 ± 16.0%. Pericardial effusion was a common finding, reported in 21 (23.3%) of patients, including moderate size effusion in 8.9% and large in 7.8%. The effusion caused tamponade in 11 (12.2%) of patients. Out of 83 patients who experienced a decrease in LVEF, 30 could be classified as takotsubo syndrome. The takotsubo patients were older than those with myocarditis, and with relatively high proportion of males. About one third of the cases was complicated by cardiogenic shock. Myocardial involvement in COVID-19 patients most often presents as a new, rapid decrease in LVEF, although normal LVEF or takotsubo-like wall motion pattern does not rule out myocarditis. Moderate and large pericardial effusion is common, and cardiac tamponade occurs in 12.2% of patients. Cardiogenic shock develops in one third of the patients. Mortality appears to be high at 26%." @default.
• W3176350855 created "2021-07-05" @default.
• W3176350855 creator A5008709171 @default.
• W3176350855 creator A5045857950 @default.
• W3176350855 creator A5046272362 @default.
• W3176350855 creator A5060789260 @default.
• W3176350855 creator A5065491912 @default.
• W3176350855 date "2021-07-02" @default.
• W3176350855 modified "2023-10-14" @default.
• W3176350855 title "Clinical variants of myocardial involvement in COVID-19-positive patients: a cumulative experience of 2020" @default.
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