Matches in SemOpenAlex for { <https://semopenalex.org/work/W3176411266> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W3176411266 abstract "Abstract Background: Local anesthetic containing adrenaline is commonly used in many operations to maintain hemostasis and prolong the duration of anesthesia. Antipsychotic drugs have an α-adrenergic receptor blocking action, and it is thought that β-adrenergic receptors predominate when adrenaline is administered in combination, thus inducing hypotension. Many general anesthetics have vasodilatory effects, and it is possible that blood pressure may decrease further if adrenaline-containing lidocaine is administered to antipsychotic users during anesthesia. This study aimed to assess the circulation dynamics in regular antipsychotics users administered adrenaline-containing lidocaine under general anesthesia in a dental procedure. Methods: Participants included 30 patients regularly using antipsychotics (butyrophenone, phenothiazine, and/or atypical antipsychotics) who were scheduled for dental treatment to be performed under general anesthesia. At five minutes after tracheal intubation, the systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), and percutaneous oxygen saturation (SpO2) were measured as a baseline. SBP, DBP, HR, and SpO2 were measured 2, 4, 6, 8, and 10 minutes after the injection of 1.8 mL of 2% lidocaine (32 mg) with 1:80,000 adrenaline (22.5 μg) into the oral cavity. Differences in the SBP, DBP, HR, and SpO2 between baseline and at each time point were analyzed using Dunnett’s test.Results: No significant changes were observed in the SBP, DBP, HR, and SpO2 compared to baseline until ten minutes after the administration of adrenaline-containing lidocaine. No adverse events were observed up to one hour after the administration of adrenaline-containing lidocaine.Conclusions: This study demonstrated that adrenaline used at the usual dose for dental treatment under general anesthesia is unlikely to affect the circulation dynamics of regular antipsychotic users." @default.
- W3176411266 created "2021-07-05" @default.
- W3176411266 creator A5008504910 @default.
- W3176411266 creator A5024660569 @default.
- W3176411266 creator A5046906594 @default.
- W3176411266 creator A5054472911 @default.
- W3176411266 creator A5056560738 @default.
- W3176411266 creator A5068230396 @default.
- W3176411266 creator A5089842531 @default.
- W3176411266 date "2020-03-16" @default.
- W3176411266 modified "2023-09-25" @default.
- W3176411266 title "Hemodynamic changes in regular antipsychotic users after adrenaline-containing lidocaine injection under general anesthesia: a prospective study" @default.
- W3176411266 doi "https://doi.org/10.21203/rs.3.rs-17266/v1" @default.
- W3176411266 hasPublicationYear "2020" @default.
- W3176411266 type Work @default.
- W3176411266 sameAs 3176411266 @default.
- W3176411266 citedByCount "0" @default.
- W3176411266 crossrefType "posted-content" @default.
- W3176411266 hasAuthorship W3176411266A5008504910 @default.
- W3176411266 hasAuthorship W3176411266A5024660569 @default.
- W3176411266 hasAuthorship W3176411266A5046906594 @default.
- W3176411266 hasAuthorship W3176411266A5054472911 @default.
- W3176411266 hasAuthorship W3176411266A5056560738 @default.
- W3176411266 hasAuthorship W3176411266A5068230396 @default.
- W3176411266 hasAuthorship W3176411266A5089842531 @default.
- W3176411266 hasBestOaLocation W31764112661 @default.
- W3176411266 hasConcept C126322002 @default.
- W3176411266 hasConcept C178853913 @default.
- W3176411266 hasConcept C2775859304 @default.
- W3176411266 hasConcept C2777953023 @default.
- W3176411266 hasConcept C2780149897 @default.
- W3176411266 hasConcept C42219234 @default.
- W3176411266 hasConcept C71924100 @default.
- W3176411266 hasConcept C84393581 @default.
- W3176411266 hasConceptScore W3176411266C126322002 @default.
- W3176411266 hasConceptScore W3176411266C178853913 @default.
- W3176411266 hasConceptScore W3176411266C2775859304 @default.
- W3176411266 hasConceptScore W3176411266C2777953023 @default.
- W3176411266 hasConceptScore W3176411266C2780149897 @default.
- W3176411266 hasConceptScore W3176411266C42219234 @default.
- W3176411266 hasConceptScore W3176411266C71924100 @default.
- W3176411266 hasConceptScore W3176411266C84393581 @default.
- W3176411266 hasLocation W31764112661 @default.
- W3176411266 hasLocation W31764112662 @default.
- W3176411266 hasOpenAccess W3176411266 @default.
- W3176411266 hasPrimaryLocation W31764112661 @default.
- W3176411266 hasRelatedWork W1986501766 @default.
- W3176411266 hasRelatedWork W1986754045 @default.
- W3176411266 hasRelatedWork W2012510818 @default.
- W3176411266 hasRelatedWork W2016910959 @default.
- W3176411266 hasRelatedWork W2033884268 @default.
- W3176411266 hasRelatedWork W2277078587 @default.
- W3176411266 hasRelatedWork W2364305752 @default.
- W3176411266 hasRelatedWork W2411264640 @default.
- W3176411266 hasRelatedWork W2412698378 @default.
- W3176411266 hasRelatedWork W4291018201 @default.
- W3176411266 isParatext "false" @default.
- W3176411266 isRetracted "false" @default.
- W3176411266 magId "3176411266" @default.
- W3176411266 workType "article" @default.