FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3176450596> ?p ?o ?g. }

• W3176450596 endingPage "16872" @default.
• W3176450596 startingPage "16859" @default.
• W3176450596 abstract "The ADAMs (a disintegrin and metalloproteinase) are a family of cell surface proteins with crucial roles in the regulation of cell adhesion, cell proliferation to migration, proteolysis and cell signaling transduction pathways. Among these enzymes, the ADAM17 shows significant effects in the “ectodomain shedding” of its substrates such as cytokines (e.g., tumor necrosis factor α, TNFα), growth factors (e.g., epidermal growth factor, EGF), adhesion proteins (e.g., L-selectin), and their receptors (e.g., IL-6R and TNFα). Several studies focus on the underlying molecular mechanisms of ADAM17 in diseased conditions. Here, we took several different approaches to elucidate the function of ADAM17, the participation of ADAM17 in several human diseases, and the potential as targeted therapy reagents. As more and more studies verify the miRNA-mediated expression variation of ADAM17, the specific regulation network of miRNAs and ADAM17 was exploited in this review as well." @default.
• W3176450596 created "2021-07-05" @default.
• W3176450596 creator A5002343596 @default.
• W3176450596 creator A5033186359 @default.
• W3176450596 creator A5036995575 @default.
• W3176450596 creator A5046247277 @default.
• W3176450596 creator A5048159118 @default.
• W3176450596 creator A5081442383 @default.
• W3176450596 date "2021-06-28" @default.
• W3176450596 modified "2023-10-18" @default.
• W3176450596 title "Molecular switch in human diseases-disintegrin and metalloproteinases, ADAM17" @default.
• W3176450596 cites W113340157 @default.
• W3176450596 cites W1534208912 @default.
• W3176450596 cites W1573349870 @default.
• W3176450596 cites W1858549592 @default.
• W3176450596 cites W1897281103 @default.
• W3176450596 cites W1965208860 @default.
• W3176450596 cites W1969333571 @default.
• W3176450596 cites W1974997620 @default.
• W3176450596 cites W1977619993 @default.
• W3176450596 cites W1979009623 @default.
• W3176450596 cites W1979583043 @default.
• W3176450596 cites W1989171408 @default.
• W3176450596 cites W1990376085 @default.
• W3176450596 cites W1990515594 @default.
• W3176450596 cites W1991888662 @default.
• W3176450596 cites W1994607862 @default.
• W3176450596 cites W1997483223 @default.
• W3176450596 cites W1997522892 @default.
• W3176450596 cites W1998646933 @default.
• W3176450596 cites W2000023267 @default.
• W3176450596 cites W2002081155 @default.
• W3176450596 cites W2003074093 @default.
• W3176450596 cites W2011601559 @default.
• W3176450596 cites W2011793282 @default.
• W3176450596 cites W2012150809 @default.
• W3176450596 cites W2012816457 @default.
• W3176450596 cites W2016247818 @default.
• W3176450596 cites W2020677206 @default.
• W3176450596 cites W2028140058 @default.
• W3176450596 cites W2030277145 @default.
• W3176450596 cites W2036842448 @default.
• W3176450596 cites W2038578669 @default.
• W3176450596 cites W2040799583 @default.
• W3176450596 cites W2046396043 @default.
• W3176450596 cites W2048356493 @default.
• W3176450596 cites W2048621255 @default.
• W3176450596 cites W2049486349 @default.
• W3176450596 cites W2051678809 @default.
• W3176450596 cites W2053555736 @default.
• W3176450596 cites W2056181922 @default.
• W3176450596 cites W2056943748 @default.
• W3176450596 cites W2057650091 @default.
• W3176450596 cites W2061593125 @default.
• W3176450596 cites W2061860615 @default.
• W3176450596 cites W2061943904 @default.
• W3176450596 cites W2064521325 @default.
• W3176450596 cites W2067775188 @default.
• W3176450596 cites W2074881372 @default.
• W3176450596 cites W2076629757 @default.
• W3176450596 cites W2078256947 @default.
• W3176450596 cites W2078269233 @default.
• W3176450596 cites W2082873628 @default.
• W3176450596 cites W2086255604 @default.
• W3176450596 cites W2090663837 @default.
• W3176450596 cites W2090685720 @default.
• W3176450596 cites W2091146331 @default.
• W3176450596 cites W2091648043 @default.
• W3176450596 cites W2094504982 @default.
• W3176450596 cites W2108728408 @default.
• W3176450596 cites W2114557056 @default.
• W3176450596 cites W2114853101 @default.
• W3176450596 cites W2119445810 @default.
• W3176450596 cites W2125478352 @default.
• W3176450596 cites W2131091972 @default.
• W3176450596 cites W2140362117 @default.
• W3176450596 cites W2160994404 @default.
• W3176450596 cites W2168779696 @default.
• W3176450596 cites W2201728328 @default.
• W3176450596 cites W2514068142 @default.
• W3176450596 cites W2550143520 @default.
• W3176450596 cites W2566924442 @default.
• W3176450596 cites W2587553356 @default.
• W3176450596 cites W2667456464 @default.
• W3176450596 cites W2736267104 @default.
• W3176450596 cites W2752800791 @default.
• W3176450596 cites W2766941260 @default.
• W3176450596 cites W2795097509 @default.
• W3176450596 cites W2885531730 @default.
• W3176450596 cites W2909004903 @default.
• W3176450596 cites W2910299825 @default.
• W3176450596 cites W2920126503 @default.
• W3176450596 cites W2926908003 @default.
• W3176450596 cites W2943168560 @default.
• W3176450596 cites W2955543470 @default.
• W3176450596 cites W2963742651 @default.
• W3176450596 cites W2985205513 @default.
• W3176450596 cites W2988338184 @default.

• next