FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3176541941> ?p ?o ?g. }

• W3176541941 endingPage "101582" @default.
• W3176541941 startingPage "101582" @default.
• W3176541941 abstract "Diabetic cardiomyopathy (DCM) is a cardiac dysfunction observed in a patient with diabetes that may lead to heart failure. No specific treatment has yet been tested in DCM. Therefore, in this study, it was investigated that the potential of thymoquinone (TYM) and beta-aminoisobutyric acid (BAIBA) to treat DCM. Five groups (n = 7) were formed, namely control, diabetes, TYM, BAIBA and TYM + BAIBA, with a random selection from 35 adult male rats. Diabetes mellitus was induced by intraperitoneal administration of 50 mg/kg streptozotocin to all groups except the control. After establishing experimental diabetes, TYM (20 mg/kg/day) and BAIBA (100 mg/kg/day) were administered alone or in combination with other groups other than the control and diabetes groups for five weeks by gavage. Serum aspartate aminotransferase, lactate dehydrogenase, creatine kinase-MB, and tissue malondialdehyde levels increased significantly, and tissue glutathione levels decreased in the diabetes group compared to the control group. An increase in the expression of tumor necrosis factor-α in the myocardium and the rate of fibrosis and apoptosis were found in the histopathological analysis. In the TYM and BAIBA groups, all pathological changes observed in the diabetes group improved significantly. The therapeutic effects of these agents on DCM are probably due to their antihyperglycemic, antidiabetic, antioxidant, and anti-inflammatory effects. The present results suggested that TYM and BAIBA have the potential therapeutic effects on DCM that were used alone or combined." @default.
• W3176541941 created "2021-07-05" @default.
• W3176541941 creator A5035855838 @default.
• W3176541941 creator A5061825369 @default.
• W3176541941 date "2021-08-01" @default.
• W3176541941 modified "2023-09-30" @default.
• W3176541941 title "The ameliorative effects of thymoquinone and beta-aminoisobutyric acid on streptozotocin-induced diabetic cardiomyopathy" @default.
• W3176541941 cites W186913681 @default.
• W3176541941 cites W1967275921 @default.
• W3176541941 cites W1977528639 @default.
• W3176541941 cites W1983310681 @default.
• W3176541941 cites W2009410829 @default.
• W3176541941 cites W2027756656 @default.
• W3176541941 cites W2059743234 @default.
• W3176541941 cites W2063576996 @default.
• W3176541941 cites W2066044766 @default.
• W3176541941 cites W2108762011 @default.
• W3176541941 cites W2118151900 @default.
• W3176541941 cites W2119304571 @default.
• W3176541941 cites W2134940699 @default.
• W3176541941 cites W2163244012 @default.
• W3176541941 cites W2230697532 @default.
• W3176541941 cites W2234033618 @default.
• W3176541941 cites W2236031153 @default.
• W3176541941 cites W2270684689 @default.
• W3176541941 cites W2285094646 @default.
• W3176541941 cites W2330945548 @default.
• W3176541941 cites W2425644022 @default.
• W3176541941 cites W2498616159 @default.
• W3176541941 cites W2608645770 @default.
• W3176541941 cites W2741151004 @default.
• W3176541941 cites W2754170368 @default.
• W3176541941 cites W2756104041 @default.
• W3176541941 cites W2760474504 @default.
• W3176541941 cites W2761954664 @default.
• W3176541941 cites W2772652485 @default.
• W3176541941 cites W2774743973 @default.
• W3176541941 cites W2792774729 @default.
• W3176541941 cites W2793795908 @default.
• W3176541941 cites W2793816672 @default.
• W3176541941 cites W2794488283 @default.
• W3176541941 cites W2795910292 @default.
• W3176541941 cites W2800919076 @default.
• W3176541941 cites W2802734636 @default.
• W3176541941 cites W2899238961 @default.
• W3176541941 cites W2899733963 @default.
• W3176541941 cites W2899938900 @default.
• W3176541941 cites W2900053361 @default.
• W3176541941 cites W2902118901 @default.
• W3176541941 cites W2903562879 @default.
• W3176541941 cites W2914104637 @default.
• W3176541941 cites W2917191057 @default.
• W3176541941 cites W2940275338 @default.
• W3176541941 cites W2953485758 @default.
• W3176541941 cites W2954601938 @default.
• W3176541941 cites W2981944063 @default.
• W3176541941 cites W3005271349 @default.
• W3176541941 cites W3013539094 @default.
• W3176541941 cites W3014935160 @default.
• W3176541941 cites W3048319835 @default.
• W3176541941 cites W3082213176 @default.
• W3176541941 cites W3118634522 @default.
• W3176541941 cites W3134433369 @default.
• W3176541941 cites W3135781899 @default.
• W3176541941 cites W3137886882 @default.
• W3176541941 cites W4211145818 @default.
• W3176541941 cites W4249505635 @default.
• W3176541941 doi "https://doi.org/10.1016/j.tice.2021.101582" @default.
• W3176541941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34171519" @default.
• W3176541941 hasPublicationYear "2021" @default.
• W3176541941 type Work @default.
• W3176541941 sameAs 3176541941 @default.
• W3176541941 citedByCount "6" @default.
• W3176541941 countsByYear W31765419412021 @default.
• W3176541941 countsByYear W31765419412022 @default.
• W3176541941 countsByYear W31765419412023 @default.
• W3176541941 crossrefType "journal-article" @default.
• W3176541941 hasAuthorship W3176541941A5035855838 @default.
• W3176541941 hasAuthorship W3176541941A5061825369 @default.
• W3176541941 hasConcept C126322002 @default.
• W3176541941 hasConcept C134018914 @default.
• W3176541941 hasConcept C160160445 @default.
• W3176541941 hasConcept C181199279 @default.
• W3176541941 hasConcept C2776151105 @default.
• W3176541941 hasConcept C2776553924 @default.
• W3176541941 hasConcept C2777318727 @default.
• W3176541941 hasConcept C2778004101 @default.
• W3176541941 hasConcept C2778198053 @default.
• W3176541941 hasConcept C2778401633 @default.
• W3176541941 hasConcept C2778797674 @default.
• W3176541941 hasConcept C2779034068 @default.
• W3176541941 hasConcept C2779280383 @default.
• W3176541941 hasConcept C2779679107 @default.
• W3176541941 hasConcept C2780159080 @default.
• W3176541941 hasConcept C538909803 @default.
• W3176541941 hasConcept C55493867 @default.
• W3176541941 hasConcept C555293320 @default.
• W3176541941 hasConcept C71924100 @default.

• next