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- W3176606055 abstract "Background: Central nervous system injury (CNSI) comprises a series of common diseases that severely affect patients’ motor function and quality of life and is associated with high disability and mortality rates. Previous studies have shown that contralateral lumbosacral nerve root transfer significantly improved the function of the paralyzed limb in rat models of CNSI. These studies showed that severing the sacral 1 nerve root (S1) did not damage the function of the ipsilateral lower extremity. Thus, we speculate that contralateral S1 nerve root transfer can improve the recovery of a paralyzed limb. Because no associated rigorously designed randomized controlled trial has evaluated the effectiveness of contralateral S1 nerve transfer thus far, we designed this clinical trial to compare the effects of this new treatment approach with those of traditional treatments in paralyzed patients after chronic CNSI." @default.
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- W3176606055 date "2021-06-01" @default.
- W3176606055 modified "2023-10-14" @default.
- W3176606055 title "Contralateral S1 nerve root transfer for motor function recovery in the lower extremity among patients with central nervous system injury: study protocol for a randomized controlled trial" @default.
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- W3176606055 doi "https://doi.org/10.21037/apm-21-183" @default.
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