FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3176910794> ?p ?o ?g. }

• W3176910794 abstract "Multiple myeloma (MM) has a five-year prevalence worldwide of 230,000 people and is known as the second most common hematological malignancy within the United States. Extensive research has been conducted to gain a wide range of treatment strategies, providing hope to these patients. Combination therapy using chemotherapy, monoclonal antibodies, and immunomodulatory drugs are the current management of choice. After the introduction of chimeric antigen receptor (CAR) T cell therapy, promising results have been evidenced. In this therapy, T cells are derived from the patient and modified in-vitro to induce receptors that later target specific antigens when they are injected into patients. CAR T cells use three mechanisms to kill tumor cells: cytolytic pathways, cytokine release, and Fas/FasL axis. In this review, we highlight the different tumor markers targeted for therapy against multiple myeloma (MM). Target antigens for CAR T cell therapy include B-cell maturation antigen (BCMA), signaling lymphocyte activation molecule F7 (SLAMF7), CD38, CD138, CD19, immunoglobulin kappa light chain, orphan G protein-coupled receptor class C group 5 member D (GPRC5D). With the benefit of improving survival and prognosis, this therapy does carry a risk of some adverse events such as cytokine release syndrome, encephalopathy, infections, hypogammaglobulinemia, and tumor lysis syndrome." @default.
• W3176910794 created "2021-07-05" @default.
• W3176910794 creator A5004408352 @default.
• W3176910794 creator A5023421834 @default.
• W3176910794 creator A5034427327 @default.
• W3176910794 creator A5051479714 @default.
• W3176910794 creator A5052144067 @default.
• W3176910794 creator A5066786575 @default.
• W3176910794 creator A5071561882 @default.
• W3176910794 creator A5074939654 @default.
• W3176910794 creator A5084946716 @default.
• W3176910794 date "2021-06-25" @default.
• W3176910794 modified "2023-10-03" @default.
• W3176910794 title "Chimeric Antigen Receptor T Cell Therapy and Its Significance in Multiple Myeloma" @default.
• W3176910794 cites W102484664 @default.
• W3176910794 cites W1607012924 @default.
• W3176910794 cites W1647507681 @default.
• W3176910794 cites W1661103064 @default.
• W3176910794 cites W1832162035 @default.
• W3176910794 cites W1986740039 @default.
• W3176910794 cites W2007480898 @default.
• W3176910794 cites W2019164609 @default.
• W3176910794 cites W2047205338 @default.
• W3176910794 cites W2072259475 @default.
• W3176910794 cites W2099570622 @default.
• W3176910794 cites W2153147430 @default.
• W3176910794 cites W2235523093 @default.
• W3176910794 cites W2335984750 @default.
• W3176910794 cites W2398722604 @default.
• W3176910794 cites W2400276917 @default.
• W3176910794 cites W2413807845 @default.
• W3176910794 cites W2471662063 @default.
• W3176910794 cites W2549396793 @default.
• W3176910794 cites W2602650330 @default.
• W3176910794 cites W2755114342 @default.
• W3176910794 cites W2800948756 @default.
• W3176910794 cites W2885496269 @default.
• W3176910794 cites W2902015040 @default.
• W3176910794 cites W2913516976 @default.
• W3176910794 cites W2921417465 @default.
• W3176910794 cites W2922471907 @default.
• W3176910794 cites W2923396001 @default.
• W3176910794 cites W2924578117 @default.
• W3176910794 cites W2943806088 @default.
• W3176910794 cites W2956329092 @default.
• W3176910794 cites W2967096120 @default.
• W3176910794 cites W2969932204 @default.
• W3176910794 cites W2974984990 @default.
• W3176910794 cites W2987013001 @default.
• W3176910794 cites W2994712982 @default.
• W3176910794 cites W3033460281 @default.
• W3176910794 cites W3158345122 @default.
• W3176910794 cites W323542206 @default.
• W3176910794 doi "https://doi.org/10.7759/cureus.15917" @default.
• W3176910794 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8310625" @default.
• W3176910794 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34322356" @default.
• W3176910794 hasPublicationYear "2021" @default.
• W3176910794 type Work @default.
• W3176910794 sameAs 3176910794 @default.
• W3176910794 citedByCount "0" @default.
• W3176910794 crossrefType "journal-article" @default.
• W3176910794 hasAuthorship W3176910794A5004408352 @default.
• W3176910794 hasAuthorship W3176910794A5023421834 @default.
• W3176910794 hasAuthorship W3176910794A5034427327 @default.
• W3176910794 hasAuthorship W3176910794A5051479714 @default.
• W3176910794 hasAuthorship W3176910794A5052144067 @default.
• W3176910794 hasAuthorship W3176910794A5066786575 @default.
• W3176910794 hasAuthorship W3176910794A5071561882 @default.
• W3176910794 hasAuthorship W3176910794A5074939654 @default.
• W3176910794 hasAuthorship W3176910794A5084946716 @default.
• W3176910794 hasBestOaLocation W31769107941 @default.
• W3176910794 hasConcept C10882517 @default.
• W3176910794 hasConcept C147483822 @default.
• W3176910794 hasConcept C1491633281 @default.
• W3176910794 hasConcept C203014093 @default.
• W3176910794 hasConcept C2776364478 @default.
• W3176910794 hasConcept C2777701055 @default.
• W3176910794 hasConcept C2778957590 @default.
• W3176910794 hasConcept C2780850621 @default.
• W3176910794 hasConcept C3875195 @default.
• W3176910794 hasConcept C502942594 @default.
• W3176910794 hasConcept C54355233 @default.
• W3176910794 hasConcept C71924100 @default.
• W3176910794 hasConcept C86803240 @default.
• W3176910794 hasConcept C8891405 @default.
• W3176910794 hasConceptScore W3176910794C10882517 @default.
• W3176910794 hasConceptScore W3176910794C147483822 @default.
• W3176910794 hasConceptScore W3176910794C1491633281 @default.
• W3176910794 hasConceptScore W3176910794C203014093 @default.
• W3176910794 hasConceptScore W3176910794C2776364478 @default.
• W3176910794 hasConceptScore W3176910794C2777701055 @default.
• W3176910794 hasConceptScore W3176910794C2778957590 @default.
• W3176910794 hasConceptScore W3176910794C2780850621 @default.
• W3176910794 hasConceptScore W3176910794C3875195 @default.
• W3176910794 hasConceptScore W3176910794C502942594 @default.
• W3176910794 hasConceptScore W3176910794C54355233 @default.
• W3176910794 hasConceptScore W3176910794C71924100 @default.
• W3176910794 hasConceptScore W3176910794C86803240 @default.
• W3176910794 hasConceptScore W3176910794C8891405 @default.
• W3176910794 hasLocation W31769107941 @default.

• next